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The lin-12 locus specifies cell fates in Caenorhabditis elegans.
Greenwald IS, Sternberg PW, Horvitz HR. Greenwald IS, et al. Cell. 1983 Sep;34(2):435-44. doi: 10.1016/0092-8674(83)90377-x. Cell. 1983. PMID: 6616618
Dominant suppressors of a muscle mutant define an essential gene of Caenorhabditis elegans.
Greenwald IS, Horvitz HR. Greenwald IS, et al. Genetics. 1982 Jun;101(2):211-25. Genetics. 1982. PMID: 7173602 Free PMC article.
unc-93(e1500): A behavioral mutant of Caenorhabditis elegans that defines a gene with a wild-type null phenotype.
Greenwald IS, Horvitz HR. Greenwald IS, et al. Genetics. 1980 Sep;96(1):147-64. Genetics. 1980. PMID: 6894129 Free PMC article.
Mutations that affect neural cell lineages and cell fates during the development of the nematode Caenorhabditis elegans.
Horvitz HR, Sternberg PW, Greenwald IS, Fixsen W, Ellis HM. Horvitz HR, et al. Among authors: greenwald is. Cold Spring Harb Symp Quant Biol. 1983;48 Pt 2:453-63. doi: 10.1101/sqb.1983.048.01.050. Cold Spring Harb Symp Quant Biol. 1983. PMID: 6586368
New positive regulators of lin-12 activity in Caenorhabditis elegans include the BRE-5/Brainiac glycosphingolipid biosynthesis enzyme.
Katic I, Vallier LG, Greenwald I. Katic I, et al. Among authors: greenwald i. Genetics. 2005 Dec;171(4):1605-15. doi: 10.1534/genetics.105.048041. Epub 2005 Sep 12. Genetics. 2005. PMID: 16157663 Free PMC article.
The molecular identification of one of the new suppressor genes revealed it as bre-5, which had previously been identified in screens for mutations that confer resistance to Bt toxin in C. elegans. bre-5 is the homolog of D. melanogaster brainiac. ...
The molecular identification of one of the new suppressor genes revealed it as bre-5, which had previously been identified in screens for mu …
A Real-Time Biosensor for ERK Activity Reveals Signaling Dynamics during C. elegans Cell Fate Specification.
de la Cova C, Townley R, Regot S, Greenwald I. de la Cova C, et al. Among authors: greenwald i. Dev Cell. 2017 Sep 11;42(5):542-553.e4. doi: 10.1016/j.devcel.2017.07.014. Epub 2017 Aug 17. Dev Cell. 2017. PMID: 28826819 Free PMC article.
Influences of LIN-12/Notch and POP-1/TCF on the Robustness of Ventral Uterine Cell Fate Specification in Caenorhabditis elegans Gonadogenesis.
Sallee MD, Aydin T, Greenwald I. Sallee MD, et al. Among authors: greenwald i. G3 (Bethesda). 2015 Oct 19;5(12):2775-82. doi: 10.1534/g3.115.022608. G3 (Bethesda). 2015. PMID: 26483009 Free PMC article.
We find evidence that lin-12 activity contributes to the robustness of βVU fate at elevated temperature, that the Caenorhabditis elegans Notch paralog glp-1 is not functionally redundant with lin-12 in specifying βVU fate, and that the activity of POP-1, the sole C. elegan …
We find evidence that lin-12 activity contributes to the robustness of βVU fate at elevated temperature, that the Caenorhabditis elegans Not …
Spatial regulation of lag-2 transcription during vulval precursor cell fate patterning in Caenorhabditis elegans.
Zhang X, Greenwald I. Zhang X, et al. Among authors: greenwald i. Genetics. 2011 Aug;188(4):847-58. doi: 10.1534/genetics.111.128389. Epub 2011 May 19. Genetics. 2011. PMID: 21596897 Free PMC article.
We find that the lag-2 promoter contains an element, VPCrep, which mediates repression in all VPCs when the inductive signal is absent, and another promoter element, VPCact, which is required for activation when repression is relieved by the inductive signal. …
We find that the lag-2 promoter contains an element, VPCrep, which mediates repression in all VPCs when the inductive signal is absen …
LIN-12/Notch signaling in C. elegans.
Greenwald I. Greenwald I. WormBook. 2005 Aug 8:1-16. doi: 10.1895/wormbook.1.10.1. WormBook. 2005. PMID: 18050403 Free PMC article. Review.
This chapter is focused on detailing how the "awesome power of C. elegans genetics" has identified many core components and modulators of LIN-12/Notch activity....
This chapter is focused on detailing how the "awesome power of C. elegans genetics" has identified many core components and modulator …
EMB-4: a predicted ATPase that facilitates lin-12 activity in Caenorhabditis elegans.
Katic I, Greenwald I. Katic I, et al. Among authors: greenwald i. Genetics. 2006 Dec;174(4):1907-15. doi: 10.1534/genetics.106.063453. Epub 2006 Oct 9. Genetics. 2006. PMID: 17030954 Free PMC article.
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