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CTLA-4 and T cell activation.
Oosterwegel MA, Greenwald RJ, Mandelbrot DA, Lorsbach RB, Sharpe AH. Oosterwegel MA, et al. Curr Opin Immunol. 1999 Jun;11(3):294-300. doi: 10.1016/s0952-7915(99)80047-8. Curr Opin Immunol. 1999. PMID: 10375557 Review.
ICOS is critical for CD40-mediated antibody class switching.
McAdam AJ, Greenwald RJ, Levin MA, Chernova T, Malenkovich N, Ling V, Freeman GJ, Sharpe AH. McAdam AJ, et al. Nature. 2001 Jan 4;409(6816):102-5. doi: 10.1038/35051107. Nature. 2001. PMID: 11343122
Deletion of a conserved Il4 silencer impairs T helper type 1-mediated immunity.
Ansel KM, Greenwald RJ, Agarwal S, Bassing CH, Monticelli S, Interlandi J, Djuretic IM, Lee DU, Sharpe AH, Alt FW, Rao A. Ansel KM, et al. Among authors: greenwald rj. Nat Immunol. 2004 Dec;5(12):1251-9. doi: 10.1038/ni1135. Epub 2004 Oct 31. Nat Immunol. 2004. PMID: 15516924
PD-L1 and PD-L2 have distinct roles in regulating host immunity to cutaneous leishmaniasis.
Liang SC, Greenwald RJ, Latchman YE, Rosas L, Satoskar A, Freeman GJ, Sharpe AH. Liang SC, et al. Among authors: greenwald rj. Eur J Immunol. 2006 Jan;36(1):58-64. doi: 10.1002/eji.200535458. Eur J Immunol. 2006. PMID: 16358363 Free article.
Rap1-GTP is a negative regulator of Th cell function and promotes the generation of CD4+CD103+ regulatory T cells in vivo.
Li L, Greenwald RJ, Lafuente EM, Tzachanis D, Berezovskaya A, Freeman GJ, Sharpe AH, Boussiotis VA. Li L, et al. Among authors: greenwald rj. J Immunol. 2005 Sep 1;175(5):3133-9. doi: 10.4049/jimmunol.175.5.3133. J Immunol. 2005. PMID: 16116203 Free article.
Cutting edge: CTLA-4 (CD152) differentially regulates mitogen-activated protein kinases (extracellular signal-regulated kinase and c-Jun N-terminal kinase) in CD4+ T cells from receptor/ligand-deficient mice.
Schneider H, Mandelbrot DA, Greenwald RJ, Ng F, Lechler R, Sharpe AH, Rudd CE. Schneider H, et al. Among authors: greenwald rj. J Immunol. 2002 Oct 1;169(7):3475-9. doi: 10.4049/jimmunol.169.7.3475. J Immunol. 2002. PMID: 12244135 Free article.
T helper differentiation in resistant and susceptible B7-deficient mice infected with Leishmania major.
Brown JA, Greenwald RJ, Scott S, Schweitzer AN, Satoskar AR, Chung C, Schopf LR, van der Woude D, Sypek JP, Sharpe AH. Brown JA, et al. Eur J Immunol. 2002 Jun;32(6):1764-72. doi: 10.1002/1521-4141(200206)32:6<1764::AID-IMMU1764>3.0.CO;2-V. Eur J Immunol. 2002. PMID: 12115660
Negative co-receptors on lymphocytes.
Greenwald RJ, Latchman YE, Sharpe AH. Greenwald RJ, et al. Curr Opin Immunol. 2002 Jun;14(3):391-6. doi: 10.1016/s0952-7915(02)00341-2. Curr Opin Immunol. 2002. PMID: 11973140 Review.
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