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Temporal multi-omics identifies LRG1 as a vascular niche instructor of metastasis.
Singhal M, Gengenbacher N, Abdul Pari AA, Kamiyama M, Hai L, Kuhn BJ, Kallenberg DM, Kulkarni SR, Camilli C, Preuß SF, Leuchs B, Mogler C, Espinet E, Besemfelder E, Heide D, Heikenwalder M, Sprick MR, Trumpp A, Krijgsveld J, Schlesner M, Hu J, Moss SE, Greenwood J, Augustin HG. Singhal M, et al. Among authors: greenwood j. Sci Transl Med. 2021 Sep;13(609):eabe6805. doi: 10.1126/scitranslmed.abe6805. Epub 2021 Sep 1. Sci Transl Med. 2021. PMID: 34516824 Free PMC article.
LRG1: an emerging player in disease pathogenesis.
Camilli C, Hoeh AE, De Rossi G, Moss SE, Greenwood J. Camilli C, et al. Among authors: greenwood j. J Biomed Sci. 2022 Jan 21;29(1):6. doi: 10.1186/s12929-022-00790-6. J Biomed Sci. 2022. PMID: 35062948 Free PMC article. Review.
LRG1 destabilizes tumor vessels and restricts immunotherapeutic potency.
O'Connor MN, Kallenberg DM, Camilli C, Pilotti C, Dritsoula A, Jackstadt R, Bowers CE, Watson HA, Alatsatianos M, Ohme J, Dowsett L, George J, Blackburn JWD, Wang X, Singhal M, Augustin HG, Ager A, Sansom OJ, Moss SE, Greenwood J. O'Connor MN, et al. Among authors: greenwood j. Med. 2021 Nov 12;2(11):1231-1252.e10. doi: 10.1016/j.medj.2021.10.002. Epub 2021 Nov 3. Med. 2021. PMID: 35590198 Free PMC article.
LRG1 promotes angiogenesis by modulating endothelial TGF-β signalling.
Wang X, Abraham S, McKenzie JAG, Jeffs N, Swire M, Tripathi VB, Luhmann UFO, Lange CAK, Zhai Z, Arthur HM, Bainbridge J, Moss SE, Greenwood J. Wang X, et al. Among authors: greenwood j. Nature. 2013 Jul 18;499(7458):306-11. doi: 10.1038/nature12345. Nature. 2013. PMID: 23868260 Free PMC article.
LRG1 as a novel therapeutic target in eye disease.
De Rossi G, Da Vitoria Lobo ME, Greenwood J, Moss SE. De Rossi G, et al. Among authors: greenwood j. Eye (Lond). 2022 Feb;36(2):328-340. doi: 10.1038/s41433-021-01807-4. Epub 2022 Jan 5. Eye (Lond). 2022. PMID: 34987199 Free PMC article. Review.
Angiopathic activity of LRG1 is induced by the IL-6/STAT3 pathway.
Dritsoula A, Dowsett L, Pilotti C, O'Connor MN, Moss SE, Greenwood J. Dritsoula A, et al. Among authors: greenwood j. Sci Rep. 2022 Mar 22;12(1):4867. doi: 10.1038/s41598-022-08516-2. Sci Rep. 2022. PMID: 35318338 Free PMC article.
Leucine-rich alpha-2-glycoprotein 1 (LRG1) as a novel ADC target.
Javaid F, Pilotti C, Camilli C, Kallenberg D, Bahou C, Blackburn J, R Baker J, Greenwood J, Moss SE, Chudasama V. Javaid F, et al. Among authors: greenwood j. RSC Chem Biol. 2021 May 31;2(4):1206-1220. doi: 10.1039/d1cb00104c. eCollection 2021 Aug 5. RSC Chem Biol. 2021. PMID: 34458833 Free PMC article.
Correction: LRG1 as a novel therapeutic target in eye disease.
De Rossi G, Da Vitoria Lobo ME, Greenwood J, Moss SE. De Rossi G, et al. Among authors: greenwood j. Eye (Lond). 2023 May;37(7):1517. doi: 10.1038/s41433-022-01988-6. Eye (Lond). 2023. PMID: 35228692 Free PMC article. No abstract available.
1,357 results