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Synthesis and antibacterial activity of U-100592 and U-100766, two oxazolidinone antibacterial agents for the potential treatment of multidrug-resistant gram-positive bacterial infections.
Brickner SJ, Hutchinson DK, Barbachyn MR, Manninen PR, Ulanowicz DA, Garmon SA, Grega KC, Hendges SK, Toops DS, Ford CW, Zurenko GE. Brickner SJ, et al. Among authors: grega kc. J Med Chem. 1996 Feb 2;39(3):673-9. doi: 10.1021/jm9509556. J Med Chem. 1996. PMID: 8576909
Design, synthesis, and evaluation of novel oxazolidinone antibacterial agents active against multidrug-resistant bacteria.
Barbachyn MR, Brickner SJ, Gadwood RC, Garmon SA, Grega KC, Hutchinson DK, Munesada K, Reischer RJ, Taniguchi M, Thomasco LM, Toops DS, Yamada H, Ford CW, Zurenko GE. Barbachyn MR, et al. Among authors: grega kc. Adv Exp Med Biol. 1998;456:219-38. doi: 10.1007/978-1-4615-4897-3_12. Adv Exp Med Biol. 1998. PMID: 10549371 Review. No abstract available.
Substituent effects on the antibacterial activity of nitrogen-carbon-linked (azolylphenyl)oxazolidinones with expanded activity against the fastidious gram-negative organisms Haemophilus influenzae and Moraxella catarrhalis.
Genin MJ, Allwine DA, Anderson DJ, Barbachyn MR, Emmert DE, Garmon SA, Graber DR, Grega KC, Hester JB, Hutchinson DK, Morris J, Reischer RJ, Ford CW, Zurenko GE, Hamel JC, Schaadt RD, Stapert D, Yagi BH. Genin MJ, et al. Among authors: grega kc. J Med Chem. 2000 Mar 9;43(5):953-70. doi: 10.1021/jm990373e. J Med Chem. 2000. PMID: 10715160
Carbon-carbon-linked (pyrazolylphenyl)oxazolidinones with antibacterial activity against multiple drug resistant gram-positive and fastidious gram-negative bacteria.
Lee CS, Allwine DA, Barbachyn MR, Grega KC, Dolak LA, Ford CW, Jensen RM, Seest EP, Hamel JC, Schaadt RD, Stapert D, Yagi BH, Zurenko GE, Genin MJ. Lee CS, et al. Among authors: grega kc. Bioorg Med Chem. 2001 Dec;9(12):3243-53. doi: 10.1016/s0968-0896(01)00233-4. Bioorg Med Chem. 2001. PMID: 11711300