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Orchestrating house dust mite-associated allergy in the lung.
Gregory LG, Lloyd CM. Gregory LG, et al. Trends Immunol. 2011 Sep;32(9):402-11. doi: 10.1016/ Epub 2011 Jul 23. Trends Immunol. 2011. PMID: 21783420 Free PMC article. Review.
Pathophysiological features of asthma develop in parallel in house dust mite-exposed neonatal mice.
Saglani S, Mathie SA, Gregory LG, Bell MJ, Bush A, Lloyd CM. Saglani S, et al. Among authors: gregory lg. Am J Respir Cell Mol Biol. 2009 Sep;41(3):281-9. doi: 10.1165/rcmb.2008-0396OC. Epub 2009 Jan 16. Am J Respir Cell Mol Biol. 2009. PMID: 19151316 Free PMC article.
Inhaled house dust mite induces pulmonary T helper 2 cytokine production.
Gregory LG, Causton B, Murdoch JR, Mathie SA, O'Donnell V, Thomas CP, Priest FM, Quint DJ, Lloyd CM. Gregory LG, et al. Clin Exp Allergy. 2009 Oct;39(10):1597-610. doi: 10.1111/j.1365-2222.2009.03302.x. Epub 2009 Jun 22. Clin Exp Allergy. 2009. PMID: 19545261 Free PMC article.
Overexpression of Smad2 drives house dust mite-mediated airway remodeling and airway hyperresponsiveness via activin and IL-25.
Gregory LG, Mathie SA, Walker SA, Pegorier S, Jones CP, Lloyd CM. Gregory LG, et al. Am J Respir Crit Care Med. 2010 Jul 15;182(2):143-54. doi: 10.1164/rccm.200905-0725OC. Epub 2010 Mar 25. Am J Respir Crit Care Med. 2010. PMID: 20339149 Free PMC article.
IL-25 drives remodelling in allergic airways disease induced by house dust mite.
Gregory LG, Jones CP, Walker SA, Sawant D, Gowers KH, Campbell GA, McKenzie AN, Lloyd CM. Gregory LG, et al. Thorax. 2013 Jan;68(1):82-90. doi: 10.1136/thoraxjnl-2012-202003. Epub 2012 Oct 23. Thorax. 2013. PMID: 23093652 Free PMC article.
Endothelin-1 directs airway remodeling and hyper-reactivity in a murine asthma model.
Gregory LG, Jones CP, Mathie SA, Pegorier S, Lloyd CM. Gregory LG, et al. Allergy. 2013 Dec;68(12):1579-88. doi: 10.1111/all.12271. Epub 2013 Oct 14. Allergy. 2013. PMID: 24117726 Free PMC article.
Alternaria-derived serine protease activity drives IL-33-mediated asthma exacerbations.
Snelgrove RJ, Gregory LG, Peiró T, Akthar S, Campbell GA, Walker SA, Lloyd CM. Snelgrove RJ, et al. Among authors: gregory lg. J Allergy Clin Immunol. 2014 Sep;134(3):583-592.e6. doi: 10.1016/j.jaci.2014.02.002. Epub 2014 Mar 15. J Allergy Clin Immunol. 2014. PMID: 24636086 Free PMC article.
γδT cells regulate chronic airway inflammation and development of airway remodelling.
Murdoch JR, Gregory LG, Lloyd CM. Murdoch JR, et al. Among authors: gregory lg. Clin Exp Allergy. 2014 Nov;44(11):1386-98. doi: 10.1111/cea.12395. Clin Exp Allergy. 2014. PMID: 25146585 Free PMC article.
Alveolar macrophages are sentinels of murine pulmonary homeostasis following inhaled antigen challenge.
Mathie SA, Dixon KL, Walker SA, Tyrrell V, Mondhe M, O'Donnell VB, Gregory LG, Lloyd CM. Mathie SA, et al. Among authors: gregory lg. Allergy. 2015 Jan;70(1):80-9. doi: 10.1111/all.12536. Epub 2014 Nov 28. Allergy. 2015. PMID: 25331546 Free PMC article.
Pediatric severe asthma with fungal sensitization is mediated by steroid-resistant IL-33.
Castanhinha S, Sherburn R, Walker S, Gupta A, Bossley CJ, Buckley J, Ullmann N, Grychtol R, Campbell G, Maglione M, Koo S, Fleming L, Gregory L, Snelgrove RJ, Bush A, Lloyd CM, Saglani S. Castanhinha S, et al. Among authors: gregory l. J Allergy Clin Immunol. 2015 Aug;136(2):312-22.e7. doi: 10.1016/j.jaci.2015.01.016. Epub 2015 Mar 5. J Allergy Clin Immunol. 2015. PMID: 25746970 Free PMC article. Clinical Trial.
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