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Regulation of virulence determinants in vitro and in vivo in Staphylococcus aureus.
Cheung AL, Bayer AS, Zhang G, Gresham H, Xiong YQ. Cheung AL, et al. Among authors: gresham h. FEMS Immunol Med Microbiol. 2004 Jan 15;40(1):1-9. doi: 10.1016/S0928-8244(03)00309-2. FEMS Immunol Med Microbiol. 2004. PMID: 14734180 Free article. Review.
Confinement-induced quorum sensing of individual Staphylococcus aureus bacteria.
Carnes EC, Lopez DM, Donegan NP, Cheung A, Gresham H, Timmins GS, Brinker CJ. Carnes EC, et al. Among authors: gresham h. Nat Chem Biol. 2010 Jan;6(1):41-5. doi: 10.1038/nchembio.264. Epub 2009 Nov 22. Nat Chem Biol. 2010. PMID: 19935660 Free PMC article.
Selective chemical inhibition of agr quorum sensing in Staphylococcus aureus promotes host defense with minimal impact on resistance.
Sully EK, Malachowa N, Elmore BO, Alexander SM, Femling JK, Gray BM, DeLeo FR, Otto M, Cheung AL, Edwards BS, Sklar LA, Horswill AR, Hall PR, Gresham HD. Sully EK, et al. Among authors: gresham hd. PLoS Pathog. 2014 Jun 12;10(6):e1004174. doi: 10.1371/journal.ppat.1004174. eCollection 2014 Jun. PLoS Pathog. 2014. PMID: 24945495 Free PMC article.
Nox2 modification of LDL is essential for optimal apolipoprotein B-mediated control of agr type III Staphylococcus aureus quorum-sensing.
Hall PR, Elmore BO, Spang CH, Alexander SM, Manifold-Wheeler BC, Castleman MJ, Daly SM, Peterson MM, Sully EK, Femling JK, Otto M, Horswill AR, Timmins GS, Gresham HD. Hall PR, et al. Among authors: gresham hd. PLoS Pathog. 2013 Feb;9(2):e1003166. doi: 10.1371/journal.ppat.1003166. Epub 2013 Feb 14. PLoS Pathog. 2013. PMID: 23459693 Free PMC article.
Apolipoprotein B Is an innate barrier against invasive Staphylococcus aureus infection.
Peterson MM, Mack JL, Hall PR, Alsup AA, Alexander SM, Sully EK, Sawires YS, Cheung AL, Otto M, Gresham HD. Peterson MM, et al. Among authors: gresham hd. Cell Host Microbe. 2008 Dec 11;4(6):555-66. doi: 10.1016/j.chom.2008.10.001. Cell Host Microbe. 2008. PMID: 19064256 Free PMC article.
Fibrinogen depletion attenuates Staphyloccocus aureus infection by preventing density-dependent virulence gene up-regulation.
Rothfork JM, Dessus-Babus S, Van Wamel WJ, Cheung AL, Gresham HD. Rothfork JM, et al. Among authors: gresham hd. J Immunol. 2003 Nov 15;171(10):5389-95. doi: 10.4049/jimmunol.171.10.5389. J Immunol. 2003. PMID: 14607942 Free article.
Survival of Staphylococcus aureus inside neutrophils contributes to infection.
Gresham HD, Lowrance JH, Caver TE, Wilson BS, Cheung AL, Lindberg FP. Gresham HD, et al. J Immunol. 2000 Apr 1;164(7):3713-22. doi: 10.4049/jimmunol.164.7.3713. J Immunol. 2000. PMID: 10725730
Inactivation of a bacterial virulence pheromone by phagocyte-derived oxidants: new role for the NADPH oxidase in host defense.
Rothfork JM, Timmins GS, Harris MN, Chen X, Lusis AJ, Otto M, Cheung AL, Gresham HD. Rothfork JM, et al. Among authors: gresham hd. Proc Natl Acad Sci U S A. 2004 Sep 21;101(38):13867-72. doi: 10.1073/pnas.0402996101. Epub 2004 Sep 7. Proc Natl Acad Sci U S A. 2004. PMID: 15353593 Free PMC article.
Spontaneous elaboration of transforming growth factor beta suppresses host defense against bacterial infection in autoimmune MRL/lpr mice.
Lowrance JH, O'Sullivan FX, Caver TE, Waegell W, Gresham HD. Lowrance JH, et al. J Exp Med. 1994 Nov 1;180(5):1693-703. doi: 10.1084/jem.180.5.1693. J Exp Med. 1994. PMID: 7964455 Free PMC article.
Our previous study implicated transforming growth factor beta (TGF-beta) in a novel acquired defect in neutrophil function in MRL/lpr but not congenic MRL/Mp-+/+ (MRL/n) mice (Gresham, H.D., C.J. ...Our data indicate that MRL/lpr mice, as compared with congenic MRL/ …
Our previous study implicated transforming growth factor beta (TGF-beta) in a novel acquired defect in neutrophil function in MRL/lpr but no …
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