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Nucleosome reorganisation in breast cancer tissues.
Jacob DR, Guiblet WM, Mamayusupova H, Shtumpf M, Ciuta I, Ruje L, Gretton S, Bikova M, Correa C, Dellow E, Agrawal SP, Shafiei N, Drobysevskaja A, Armstrong CM, Lam JDG, Vainshtein Y, Clarkson CT, Thorn GJ, Sohn K, Pradeepa MM, Chandrasekharan S, Brooke GN, Klenova E, Zhurkin VB, Teif VB. Jacob DR, et al. Among authors: gretton s. Clin Epigenetics. 2024 Apr 1;16(1):50. doi: 10.1186/s13148-024-01656-4. Clin Epigenetics. 2024. PMID: 38561804 Free PMC article.
Engineering hemoglobin to enable homogenous PEGylation without modifying protein functionality.
Cooper CE , Silkstone GGA , Simons M , Gretton S , Rajagopal BS , Allen-Baume V , Syrett N , Shaik T , Popa G , Sheng X , Bird M , Choi JW , Piano R , Ronda L , Bettati S , Paredi G , Mozzarelli A , Reeder BJ . Cooper CE , et al. Among authors: gretton s. Biomater Sci. 2020 Jul 21;8(14):3896-3906. doi: 10.1039/c9bm01773a. Epub 2020 Jun 15. Biomater Sci. 2020. PMID: 32539053
Engineering tyrosine residues into hemoglobin enhances heme reduction, decreases oxidative stress and increases vascular retention of a hemoglobin based blood substitute.
Cooper CE, Silkstone GGA, Simons M, Rajagopal B, Syrett N, Shaik T, Gretton S, Welbourn E, Bülow L, Eriksson NL, Ronda L, Mozzarelli A, Eke A, Mathe D, Reeder BJ. Cooper CE, et al. Among authors: gretton s. Free Radic Biol Med. 2019 Apr;134:106-118. doi: 10.1016/j.freeradbiomed.2018.12.030. Epub 2018 Dec 27. Free Radic Biol Med. 2019. PMID: 30594736 Free PMC article.
Comparison of the oxidative reactivity of recombinant fetal and adult human hemoglobin: implications for the design of hemoglobin-based oxygen carriers.
Simons M, Gretton S, Silkstone GGA, Rajagopal BS, Allen-Baume V, Syrett N, Shaik T, Leiva-Eriksson N, Ronda L, Mozzarelli A, Strader MB, Alayash AI, Reeder BJ, Cooper CE. Simons M, et al. Among authors: gretton s. Biosci Rep. 2018 Jul 2;38(4):BSR20180370. doi: 10.1042/BSR20180370. Print 2018 Aug 31. Biosci Rep. 2018. PMID: 29802155 Free PMC article.
26 results