Gribkoff VK - Search Results

1

Pharmacological activation and inhibition of Slack (Slo2.2) channels.

Yang B, Gribkoff VK, Pan J, Damagnez V, Dworetzky SI, Boissard CG, Bhattacharjee A, Yan Y, Sigworth FJ, Kaczmarek LK. Yang B, et al. Among authors: gribkoff vk. Neuropharmacology. 2006 Sep;51(4):896-906. doi: 10.1016/j.neuropharm.2006.06.003. Epub 2006 Jul 28. Neuropharmacology. 2006. PMID: 16876206

2

The need for new approaches in CNS drug discovery: Why drugs have failed, and what can be done to improve outcomes.

Gribkoff VK, Kaczmarek LK. Gribkoff VK, et al. Neuropharmacology. 2017 Jul 1;120:11-19. doi: 10.1016/j.neuropharm.2016.03.021. Epub 2016 Mar 12. Neuropharmacology. 2017. PMID: 26979921 Free PMC article. Review.

3

Formation of intermediate-conductance calcium-activated potassium channels by interaction of Slack and Slo subunits.

Joiner WJ, Tang MD, Wang LY, Dworetzky SI, Boissard CG, Gan L, Gribkoff VK, Kaczmarek LK. Joiner WJ, et al. Among authors: gribkoff vk. Nat Neurosci. 1998 Oct;1(6):462-9. doi: 10.1038/2176. Nat Neurosci. 1998. PMID: 10196543

4

4,5-diphenyltriazol-3-ones: openers of large-conductance Ca(2+)-activated potassium (maxi-K) channels.

Romine JL, Martin SW, Gribkoff VK, Boissard CG, Dworetzky SI, Natale J, Li Y, Gao Q, Meanwell NA, Starrett JE Jr. Romine JL, et al. Among authors: gribkoff vk. J Med Chem. 2002 Jul 4;45(14):2942-52. doi: 10.1021/jm010569q. J Med Chem. 2002. PMID: 12086481

5

Novel openers of Ca2+-dependent large-conductance potassium channels: symmetrical pharmacophore and electrophysiological evaluation of bisphenols.

Li Y, Johnson G, Romine JL, Meanwell NA, Martin SW, Dworetzky SI, Boissard CG, Gribkoff VK, Starrett JE Jr. Li Y, et al. Among authors: gribkoff vk. Bioorg Med Chem Lett. 2003 Apr 17;13(8):1437-9. doi: 10.1016/s0960-894x(03)00156-2. Bioorg Med Chem Lett. 2003. PMID: 12668007

6

The effects of the adenosine reuptake inhibitor soluflazine on synaptic potentials and population hypoxic depolarizations in area CA1 of rat hippocampus in vitro.

Boissard CG, Gribkoff VK. Boissard CG, et al. Among authors: gribkoff vk. Neuropharmacology. 1993 Feb;32(2):149-55. doi: 10.1016/0028-3908(93)90095-k. Neuropharmacology. 1993. PMID: 8383814

7

Use-dependent blockade of Cav2.2 voltage-gated calcium channels for neuropathic pain.

Winquist RJ, Pan JQ, Gribkoff VK. Winquist RJ, et al. Among authors: gribkoff vk. Biochem Pharmacol. 2005 Aug 15;70(4):489-99. doi: 10.1016/j.bcp.2005.04.035. Biochem Pharmacol. 2005. PMID: 15950195 Review.

8

The synthesis and characterization of BMS-204352 (MaxiPost) and related 3-fluorooxindoles as openers of maxi-K potassium channels.

Hewawasam P, Gribkoff VK, Pendri Y, Dworetzky SI, Meanwell NA, Martinez E, Boissard CG, Post-Munson DJ, Trojnacki JT, Yeleswaram K, Pajor LM, Knipe J, Gao Q, Perrone R, Starrett JE Jr. Hewawasam P, et al. Among authors: gribkoff vk. Bioorg Med Chem Lett. 2002 Apr 8;12(7):1023-6. doi: 10.1016/s0960-894x(02)00101-4. Bioorg Med Chem Lett. 2002. PMID: 11909708

9

The synthesis and structure-activity relationships of 4-aryl-3-aminoquinolin-2-ones: a new class of calcium-dependent, large conductance, potassium (maxi-K) channel openers targeted for post-stroke neuroprotection.

Hewawasam P, Fan W, Knipe J, Moon SL, Boissard CG, Gribkoff VK, Starrett JE. Hewawasam P, et al. Among authors: gribkoff vk. Bioorg Med Chem Lett. 2002 Jul 8;12(13):1779-83. doi: 10.1016/s0960-894x(02)00240-8. Bioorg Med Chem Lett. 2002. PMID: 12067560

10

The synthesis and structure-activity relationships of 3-amino-4-benzylquinolin-2-ones; discovery of novel KCNQ2 channel openers.

Hewawasam P, Chen N, Ding M, Natale JT, Boissard CG, Yeola S, Gribkoff VK, Starrett J, Dworetzky SI. Hewawasam P, et al. Among authors: gribkoff vk. Bioorg Med Chem Lett. 2004 Apr 5;14(7):1615-8. doi: 10.1016/j.bmcl.2004.01.073. Bioorg Med Chem Lett. 2004. PMID: 15026035

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