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Melanocortin MC₄ receptor agonists counteract late inflammatory and apoptotic responses and improve neuronal functionality after cerebral ischemia.
Spaccapelo L, Bitto A, Galantucci M, Ottani A, Irrera N, Minutoli L, Altavilla D, Novellino E, Grieco P, Zaffe D, Squadrito F, Giuliani D, Guarini S. Spaccapelo L, et al. Among authors: grieco p. Eur J Pharmacol. 2011 Nov 30;670(2-3):479-86. doi: 10.1016/j.ejphar.2011.09.015. Epub 2011 Sep 21. Eur J Pharmacol. 2011. PMID: 21946115
Selective melanocortin MC4 receptor agonists reverse haemorrhagic shock and prevent multiple organ damage.
Giuliani D, Mioni C, Bazzani C, Zaffe D, Botticelli AR, Capolongo S, Sabba A, Galantucci M, Iannone A, Grieco P, Novellino E, Colombo G, Tomasi A, Catania A, Guarini S. Giuliani D, et al. Among authors: grieco p. Br J Pharmacol. 2007 Mar;150(5):595-603. doi: 10.1038/sj.bjp.0707115. Epub 2007 Jan 22. Br J Pharmacol. 2007. PMID: 17245369 Free PMC article.
A novel quinone-based derivative (DTNQ-Pro) induces apoptotic death via modulation of heat shock protein expression in Caco-2 cells.
Gomez-Monterrey I, Campiglia P, Bertamino A, Aquino C, Sala M, Grieco P, Dicitore A, Vanacore D, Porta A, Maresca B, Novellino E, Stiuso P. Gomez-Monterrey I, et al. Among authors: grieco p. Br J Pharmacol. 2010 Jun;160(4):931-40. doi: 10.1111/j.1476-5381.2010.00718.x. Br J Pharmacol. 2010. PMID: 20590589 Free PMC article.
Urotensin-II receptor peptide agonists.
Carotenuto A, Grieco P, Novellino E, Rovero P. Carotenuto A, et al. Among authors: grieco p. Med Res Rev. 2004 Sep;24(5):577-88. doi: 10.1002/med.20001. Med Res Rev. 2004. PMID: 15224381 Review.
239 results