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The hypoglycemic and renal protective effects of Grifola frondosa polysaccharides in early diabetic nephropathy.
Jiang T, Wang L, Ma A, Wu Y, Wu Q, Wu Q, Lu J, Zhong T. Jiang T, et al. J Food Biochem. 2020 Dec;44(12):e13515. doi: 10.1111/jfbc.13515. Epub 2020 Oct 11. J Food Biochem. 2020. PMID: 33043487
Grifola frondosa is a basidiomycete polypore fungus. Polysaccharides from G. frondosa (PGF) has recently attracted attention for its various physiological activities including antioxidant, antitumor, and anti-fatigue effects. In this study, hypoglycemic …
Grifola frondosa is a basidiomycete polypore fungus. Polysaccharides from G. frondosa (PGF) has recently attracted atte …
Hypoglycemic and hypolipidemic activities of Grifola frondosa polysaccharides and their relationships with the modulation of intestinal microflora in diabetic mice induced by high-fat diet and streptozotocin.
Guo WL, Deng JC, Pan YY, Xu JX, Hong JL, Shi FF, Liu GL, Qian M, Bai WD, Zhang W, Liu B, Zhang YY, Luo PJ, Ni L, Rao PF, Lv XC. Guo WL, et al. Int J Biol Macromol. 2020 Jun 15;153:1231-1240. doi: 10.1016/j.ijbiomac.2019.10.253. Epub 2019 Nov 20. Int J Biol Macromol. 2020. PMID: 31759027
This study aimed to investigate the hypoglycemic and hypolipidemic activities of polysaccharides from Grifola frondosa (GFP) in diabetic mice induced by high-fat diet (HFD) and streptozotocin (STZ). ...
This study aimed to investigate the hypoglycemic and hypolipidemic activities of polysaccharides from Grifola frondosa …
Preparation of a novel Grifola frondosa polysaccharide-chromium (III) complex and its hypoglycemic and hypolipidemic activities in high fat diet and streptozotocin-induced diabetic mice.
Guo WL, Shi FF, Li L, Xu JX, Chen M, Wu L, Hong JL, Qian M, Bai WD, Liu B, Zhang YY, Ni L, Rao PF, Lv XC. Guo WL, et al. Int J Biol Macromol. 2019 Jun 15;131:81-88. doi: 10.1016/j.ijbiomac.2019.03.042. Epub 2019 Mar 7. Int J Biol Macromol. 2019. PMID: 30851330
Polysaccharide from Grifola frondosa is one of the best metal-ion chelating agents because of its structural characteristics and excellent functional activities. In this study, we synthesized and characterized a novel Grifola frondosa polysaccha …
Polysaccharide from Grifola frondosa is one of the best metal-ion chelating agents because of its structural characteri …
Grifola frondosa polysaccharide: a review of antitumor and other biological activity studies in China.
He Y, Li X, Hao C, Zeng P, Zhang M, Liu Y, Chang Y, Zhang L. He Y, et al. Discov Med. 2018 Apr;25(138):159-176. Discov Med. 2018. PMID: 29723488 Free article. Review.
Grifola frondosa, a species of Basidiomycotina, is an edible medicinal mushroom with a large fruiting body characterized by overlapping caps. The beta-glucan is the major biologically active component in G. frondosa polysaccharide (GFP) or D-fraction, which h …
Grifola frondosa, a species of Basidiomycotina, is an edible medicinal mushroom with a large fruiting body characterized by ov …
Hypoglycemic activity and gut microbiota regulation of a novel polysaccharide from Grifola frondosa in type 2 diabetic mice.
Chen Y, Liu D, Wang D, Lai S, Zhong R, Liu Y, Yang C, Liu B, Sarker MR, Zhao C. Chen Y, et al. Food Chem Toxicol. 2019 Apr;126:295-302. doi: 10.1016/j.fct.2019.02.034. Epub 2019 Feb 28. Food Chem Toxicol. 2019. PMID: 30826407
GFP-N could activate insulin receptor substrate 1, phosphatidylinositol-3-kinase, and glucose transporter 4 and inhibit c-Jun N-terminal kinase 1/2 for hypoglycemic effects in diabetic mouse livers. This is also the first report of the regulatory efficacy of Grifola …
GFP-N could activate insulin receptor substrate 1, phosphatidylinositol-3-kinase, and glucose transporter 4 and inhibit c-Jun N-terminal kin …
Hypoglycemic activity of Grifola frondosa rich in vanadium.
Cui B, Han L, Qu J, Lv Y. Cui B, et al. Biol Trace Elem Res. 2009 Nov;131(2):186-91. doi: 10.1007/s12011-009-8355-4. Epub 2009 Mar 13. Biol Trace Elem Res. 2009. PMID: 19283341
The hypoglycemic activity of fermented mushroom of Grifola frondosa rich in vanadium (GFRV) was studied in this paper. ...Also, the bodyweight of the alloxan-induced hyperglycemic mice was increased gradually. In the fermented mushroom of G. frondosa, …
The hypoglycemic activity of fermented mushroom of Grifola frondosa rich in vanadium (GFRV) was studied in this paper. …
Hypoglycemic effects of Grifola frondosa (Maitake) polysaccharides F2 and F3 through improvement of insulin resistance in diabetic rats.
Xiao C, Wu Q, Xie Y, Zhang J, Tan J. Xiao C, et al. Food Funct. 2015 Nov;6(11):3567-75. doi: 10.1039/c5fo00497g. Epub 2015 Aug 27. Food Funct. 2015. PMID: 26311233
Our laboratory has previously demonstrated that Grifola frondosa polysaccharides (GFPs) showed hypoglycemic effects. This study aimed to investigate which polysaccharide-enriched fractions of GFPs were the main active constituents, and to disclose their hy …
Our laboratory has previously demonstrated that Grifola frondosa polysaccharides (GFPs) showed hypoglycemic effects. Th …
Network Pharmacology-Based Elucidation of the Hypoglycemic Mechanism of Grifola frondosa GF5000 Polysaccharides via GCK modulation in Diabetic Rats.
Xiao C, Jiao C, Huang L, Hu H, Xie Y, Wu Q. Xiao C, et al. Nutrients. 2025 Mar 10;17(6):964. doi: 10.3390/nu17060964. Nutrients. 2025. PMID: 40289960 Free PMC article.
BACKGROUND/OBJECTIVES: Our lab has previously reported that Grifola frondosa (maitake mushroom) GF5000 has antidiabetic potential owing to its ability to improve insulin resistance. This study aimed to gain insight into the system-level hypoglycemic mechanism …
BACKGROUND/OBJECTIVES: Our lab has previously reported that Grifola frondosa (maitake mushroom) GF5000 has antidiabetic potent …
Hypoglycemic and hypolipidemic mechanism of organic chromium derived from chelation of Grifola frondosa polysaccharide-chromium (III) and its modulation of intestinal microflora in high fat-diet and STZ-induced diabetic mice.
Guo WL, Chen M, Pan WL, Zhang Q, Xu JX, Lin YC, Li L, Liu B, Bai WD, Zhang YY, Ni L, Rao PF, Lv XC. Guo WL, et al. Int J Biol Macromol. 2020 Feb 15;145:1208-1218. doi: 10.1016/j.ijbiomac.2019.09.206. Epub 2019 Nov 11. Int J Biol Macromol. 2020. PMID: 31726162
Polysaccharide from Grifola frondosa is an excellent metal-ion chelating agent owing to its distinctive structure and outstanding functional activities. ...The purpose of present research was to reveal the hypoglycemic and hypolipidemic mechanism of GFP-Cr(II …
Polysaccharide from Grifola frondosa is an excellent metal-ion chelating agent owing to its distinctive structure and outstand …
The role of Rho1 gene in the cell wall integrity and polysaccharides biosynthesis of the edible mushroom Grifola frondosa.
Zan XY, Zhu HA, Jiang LH, Liang YY, Sun WJ, Tao TL, Cui FJ. Zan XY, et al. Int J Biol Macromol. 2020 Dec 15;165(Pt A):1593-1603. doi: 10.1016/j.ijbiomac.2020.09.239. Epub 2020 Oct 5. Int J Biol Macromol. 2020. PMID: 33031851
Grifola frondosa polysaccharides, especially beta-glucans, showed the significant antitumor, hypoglycemic, and immune-stimulating activities. ...Over-expression of gfRho1 improved mycelial growth rate and polysaccharide production of G. frondosa. Our s …
Grifola frondosa polysaccharides, especially beta-glucans, showed the significant antitumor, hypoglycemic, and immune-s …
43 results