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The ER-mitochondria interface: the social network of cell death.
Grimm S. Grimm S. Biochim Biophys Acta. 2012 Feb;1823(2):327-34. doi: 10.1016/j.bbamcr.2011.11.018. Epub 2011 Dec 13. Biochim Biophys Acta. 2012. PMID: 22182703 Review.
Powerhouse down: Complex II dissociation in the respiratory chain.
Hwang MS, Rohlena J, Dong LF, Neuzil J, Grimm S. Hwang MS, et al. Mitochondrion. 2014 Nov;19 Pt A:20-8. doi: 10.1016/j.mito.2014.06.001. Epub 2014 Jun 13. Mitochondrion. 2014. PMID: 24933571 Review.
CKMT1 regulates the mitochondrial permeability transition pore in a process that provides evidence for alternative forms of the complex.
Datler C, Pazarentzos E, Mahul-Mellier AL, Chaisaklert W, Hwang MS, Osborne F, Grimm S. Datler C, et al. J Cell Sci. 2014 Apr 15;127(Pt 8):1816-28. doi: 10.1242/jcs.140467. Epub 2014 Feb 12. J Cell Sci. 2014. PMID: 24522192 Free PMC article.
Respiratory chain complex II as general sensor for apoptosis.
Grimm S. Grimm S. Biochim Biophys Acta. 2013 May;1827(5):565-72. doi: 10.1016/j.bbabio.2012.09.009. Epub 2012 Sep 18. Biochim Biophys Acta. 2013. PMID: 23000077 Review.
Dissecting mitochondrial apoptosis pathways by gain-of-function cell culture screens.
Grimm S. Grimm S. Mitochondrion. 2013 May;13(3):189-94. doi: 10.1016/j.mito.2012.06.001. Epub 2012 Jun 9. Mitochondrion. 2013. PMID: 22691408 Review.
While more primitive organism such as Caenorhabditis elegans and Drosophila melanogaster feature a limited, and by now probably mostly known, array of basic cell death factors, the mammalian cell is replete with additional regulators of the cell's demise. ...
While more primitive organism such as Caenorhabditis elegans and Drosophila melanogaster feature a limited, and by now probably mostly known …
De-ubiquitinating proteases USP2a and USP2c cause apoptosis by stabilising RIP1.
Mahul-Mellier AL, Datler C, Pazarentzos E, Lin B, Chaisaklert W, Abuali G, Grimm S. Mahul-Mellier AL, et al. Biochim Biophys Acta. 2012 Aug;1823(8):1353-65. doi: 10.1016/j.bbamcr.2012.05.022. Epub 2012 May 30. Biochim Biophys Acta. 2012. PMID: 22659130
Consequently, we focussed our studies on USP2a and found that TRAF2 inhibits USP2a's effect on K48- but not on K63-linked ubiquitin chains. ...
Consequently, we focussed our studies on USP2a and found that TRAF2 inhibits USP2a's effect on K48- but not on K63-linked ubiquitin c …
Anticancer genes: inducers of tumour-specific cell death signalling.
Grimm S, Noteborn M. Grimm S, et al. Trends Mol Med. 2010 Feb;16(2):88-96. doi: 10.1016/j.molmed.2009.12.002. Trends Mol Med. 2010. PMID: 20138582 Review.
The permeability transition pore in cell death.
Grimm S, Brdiczka D. Grimm S, et al. Apoptosis. 2007 May;12(5):841-55. doi: 10.1007/s10495-007-0747-3. Apoptosis. 2007. PMID: 17453156 Review.
Genetic cell culture screens reveal mitochondrial apoptosis control.
Grimm S, Lin B. Grimm S, et al. Front Biosci (Landmark Ed). 2009 Jan 1;14:1471-8. doi: 10.2741/3318. Front Biosci (Landmark Ed). 2009. PMID: 19273140 Review.
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