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A phase 2 trial of R1507, a monoclonal antibody to the insulin-like growth factor-1 receptor (IGF-1R), in patients with recurrent or refractory rhabdomyosarcoma, osteosarcoma, synovial sarcoma, and other soft tissue sarcomas: results of a Sarcoma Alliance for Research Through Collaboration study.
Pappo AS, Vassal G, Crowley JJ, Bolejack V, Hogendoorn PC, Chugh R, Ladanyi M, Grippo JF, Dall G, Staddon AP, Chawla SP, Maki RG, Araujo DM, Geoerger B, Ganjoo K, Marina N, Blay JY, Schuetze SM, Chow WA, Helman LJ. Pappo AS, et al. Among authors: grippo jf. Cancer. 2014 Aug 15;120(16):2448-56. doi: 10.1002/cncr.28728. Epub 2014 May 2. Cancer. 2014. PMID: 24797726 Free PMC article. Clinical Trial.
Pharmacokinetically guided phase 1 trial of the IGF-1 receptor antagonist RG1507 in children with recurrent or refractory solid tumors.
Bagatell R, Herzog CE, Trippett TM, Grippo JF, Cirrincione-Dall G, Fox E, Macy M, Bish J, Whitcomb P, Aikin A, Wright G, Yurasov S, Balis FM, Gore L. Bagatell R, et al. Among authors: grippo jf. Clin Cancer Res. 2011 Feb 1;17(3):611-9. doi: 10.1158/1078-0432.CCR-10-1731. Epub 2010 Dec 2. Clin Cancer Res. 2011. PMID: 21127194 Free PMC article. Clinical Trial.
Reply.
Wat C, Gane E, Yuen MF, Pavlovic V, Mueller H, Krippendorff BF, Grippo JF, Ottosen S. Wat C, et al. Among authors: grippo jf. Hepatology. 2022 Apr;75(4):1050-1051. doi: 10.1002/hep.32113. Epub 2021 Dec 13. Hepatology. 2022. PMID: 34396570 No abstract available.
Clinical Study of Single-Stranded Oligonucleotide RO7062931 in Healthy Volunteers and Patients With Chronic Hepatitis B.
Gane E, Yuen MF, Kim DJ, Chan HL, Surujbally B, Pavlovic V, Das S, Triyatni M, Kazma R, Grippo JF, Buatois S, Lemenuel-Diot A, Krippendorff BF, Mueller H, Zhang Y, Kim HJ, Leerapun A, Lim TH, Lim YS, Tanwandee T, Kim W, Cheng W, Hu TH, Wat C. Gane E, et al. Among authors: grippo jf. Hepatology. 2021 Oct;74(4):1795-1808. doi: 10.1002/hep.31920. Epub 2021 Aug 25. Hepatology. 2021. PMID: 34037271 Free PMC article. Clinical Trial.
Clinical Pharmacokinetics of Vemurafenib.
Zhang W, Heinzmann D, Grippo JF. Zhang W, et al. Among authors: grippo jf. Clin Pharmacokinet. 2017 Sep;56(9):1033-1043. doi: 10.1007/s40262-017-0523-7. Clin Pharmacokinet. 2017. PMID: 28255850 Review.
69 results