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An enzyme in the kynurenine pathway that governs vulnerability to suicidal behavior by regulating excitotoxicity and neuroinflammation.
Brundin L, Sellgren CM, Lim CK, Grit J, Pålsson E, Landén M, Samuelsson M, Lundgren K, Brundin P, Fuchs D, Postolache TT, Traskman-Bendz L, Guillemin GJ, Erhardt S. Brundin L, et al. Among authors: grit j. Transl Psychiatry. 2016 Aug 2;6(8):e865. doi: 10.1038/tp.2016.133. Transl Psychiatry. 2016. PMID: 27483383 Free PMC article.
Ascertaining Whether Suicides Are Caused by Infections.
Brundin LC, Grit J. Brundin LC, et al. Among authors: grit j. JAMA Psychiatry. 2016 Sep 1;73(9):895-6. doi: 10.1001/jamapsychiatry.2016.1470. JAMA Psychiatry. 2016. PMID: 27533721 No abstract available.
Genomic Status of MET Potentiates Sensitivity to MET and MEK Inhibition in NF1-Related Malignant Peripheral Nerve Sheath Tumors.
Peacock JD, Pridgeon MG, Tovar EA, Essenburg CJ, Bowman M, Madaj Z, Koeman J, Boguslawski EA, Grit J, Dodd RD, Khachaturov V, Cardona DM, Chen M, Kirsch DG, Maina F, Dono R, Winn ME, Graveel CR, Steensma MR. Peacock JD, et al. Among authors: grit j. Cancer Res. 2018 Jul 1;78(13):3672-3687. doi: 10.1158/0008-5472.CAN-17-3167. Epub 2018 May 2. Cancer Res. 2018. PMID: 29720369 Free PMC article.
An inflammatory profile linked to increased suicide risk.
Keaton SA, Madaj ZB, Heilman P, Smart L, Grit J, Gibbons R, Postolache TT, Roaten K, Achtyes ED, Brundin L. Keaton SA, et al. Among authors: grit j. J Affect Disord. 2019 Mar 15;247:57-65. doi: 10.1016/j.jad.2018.12.100. Epub 2019 Jan 3. J Affect Disord. 2019. PMID: 30654266 Free PMC article.
Altered Tryptophan Catabolism in Placentas From Women With Pre-eclampsia.
Keaton SA, Heilman P, Bryleva EY, Madaj Z, Krzyzanowski S, Grit J, Miller ES, Jälmby M, Kalapotharakos G, Racicot K, Fazleabas A, Hansson SR, Brundin L. Keaton SA, et al. Among authors: grit j. Int J Tryptophan Res. 2019 Apr 8;12:1178646919840321. doi: 10.1177/1178646919840321. eCollection 2019. Int J Tryptophan Res. 2019. PMID: 31007529 Free PMC article.
p53 modulates kinase inhibitor resistance and lineage plasticity in NF1-related MPNSTs.
Grit JL, McGee LE, Tovar EA, Essenburg CJ, Wolfrum E, Beddows I, Williams K, Sheridan RTC, Schipper JL, Adams M, Arumugam M, Vander Woude T, Gurunathan S, Field JM, Wulfkuhle J, Petricoin EF 3rd, Graveel CR, Steensma MR. Grit JL, et al. Oncogene. 2024 Mar 13. doi: 10.1038/s41388-024-03000-9. Online ahead of print. Oncogene. 2024. PMID: 38480916
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