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231 results
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Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG.
Shibutani S, Takeshita M, Grollman AP. Shibutani S, et al. Among authors: grollman ap. Nature. 1991 Jan 31;349(6308):431-4. doi: 10.1038/349431a0. Nature. 1991. PMID: 1992344
Catalytic mechanism of Escherichia coli endonuclease VIII: roles of the intercalation loop and the zinc finger.
Kropachev KY, Zharkov DO, Grollman AP. Kropachev KY, et al. Among authors: grollman ap. Biochemistry. 2006 Oct 3;45(39):12039-49. doi: 10.1021/bi060663e. Biochemistry. 2006. PMID: 17002303 Free PMC article.
Active destabilization of base pairs by a DNA glycosylase wedge initiates damage recognition.
Kuznetsov NA, Bergonzo C, Campbell AJ, Li H, Mechetin GV, de los Santos C, Grollman AP, Fedorova OS, Zharkov DO, Simmerling C. Kuznetsov NA, et al. Among authors: grollman ap. Nucleic Acids Res. 2015 Jan;43(1):272-81. doi: 10.1093/nar/gku1300. Epub 2014 Dec 17. Nucleic Acids Res. 2015. PMID: 25520195 Free PMC article.
Combining structural and bioinformatics methods for the analysis of functionally important residues in DNA glycosylases.
Zharkov DO, Grollman AP. Zharkov DO, et al. Among authors: grollman ap. Free Radic Biol Med. 2002 Jun 15;32(12):1254-63. doi: 10.1016/s0891-5849(02)00828-6. Free Radic Biol Med. 2002. PMID: 12057763 Review.
Extrachromosomal unequal homologous recombination and gene conversion in simian kidney cells: effects of UV damage.
Gening L, Takeshita M, Levine RL, Peden KW, Grollman AP. Gening L, et al. Among authors: grollman ap. Mutat Res. 1998 Feb;407(1):11-24. doi: 10.1016/s0921-8777(97)00051-7. Mutat Res. 1998. PMID: 9539977
Mutagenesis induced by a single 1,N6-ethenodeoxyadenosine adduct in human cells.
Levine RL, Yang IY, Hossain M, Pandya GA, Grollman AP, Moriya M. Levine RL, et al. Among authors: grollman ap. Cancer Res. 2000 Aug 1;60(15):4098-104. Cancer Res. 2000. PMID: 10945616
Mutagenesis by 8-oxoguanine: an enemy within.
Grollman AP, Moriya M. Grollman AP, et al. Trends Genet. 1993 Jul;9(7):246-9. doi: 10.1016/0168-9525(93)90089-z. Trends Genet. 1993. PMID: 8379000 Review.
Mutations in the mutY gene of Escherichia coli enhance the frequency of targeted G:C-->T:a transversions induced by a single 8-oxoguanine residue in single-stranded DNA.
Moriya M, Grollman AP. Moriya M, et al. Among authors: grollman ap. Mol Gen Genet. 1993 May;239(1-2):72-6. doi: 10.1007/BF00281603. Mol Gen Genet. 1993. PMID: 8510665
Inhibition of cellular thymidylate synthesis by cytotoxic propenal derivatives of pyrimidine bases and deoxynucleosides.
Kalman TI, Marinelli ER, Xu B, Reddy AR, Johnson F, Grollman AP. Kalman TI, et al. Among authors: grollman ap. Biochem Pharmacol. 1991 Jul 5;42(2):431-7. doi: 10.1016/0006-2952(91)90732-k. Biochem Pharmacol. 1991. PMID: 1713460
Solution structure of an oligodeoxynucleotide duplex containing the exocyclic lesion 3,N4-etheno-2'-deoxycytidine opposite 2'-deoxyadenosine, determined by NMR spectroscopy and restrained molecular dynamics.
Korobka A, Cullinan D, Cosman M, Grollman AP, Patel DJ, Eisenberg M, de los Santos C. Korobka A, et al. Among authors: grollman ap. Biochemistry. 1996 Oct 15;35(41):13310-8. doi: 10.1021/bi9605696. Biochemistry. 1996. PMID: 8873597
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