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Antineoplastic effects of peroxisome proliferator-activated receptor gamma agonists.
Grommes C, Landreth GE, Heneka MT. Grommes C, et al. Lancet Oncol. 2004 Jul;5(7):419-29. doi: 10.1016/S1470-2045(04)01509-8. Lancet Oncol. 2004. PMID: 15231248 Review.
The elderly left behind-changes in survival trends of primary central nervous system lymphoma over the past 4 decades.
Mendez JS, Ostrom QT, Gittleman H, Kruchko C, DeAngelis LM, Barnholtz-Sloan JS, Grommes C. Mendez JS, et al. Among authors: grommes c. Neuro Oncol. 2018 Apr 9;20(5):687-694. doi: 10.1093/neuonc/nox187. Neuro Oncol. 2018. PMID: 29036697 Free PMC article.
Inverse association of PPARĪ³ agonists use and high grade glioma development.
Grommes C, Conway DS, Alshekhlee A, Barnholtz-Sloan JS. Grommes C, et al. J Neurooncol. 2010 Nov;100(2):233-9. doi: 10.1007/s11060-010-0185-x. Epub 2010 May 5. J Neurooncol. 2010. PMID: 20443132
Inhibition of in vivo glioma growth and invasion by peroxisome proliferator-activated receptor gamma agonist treatment.
Grommes C, Landreth GE, Sastre M, Beck M, Feinstein DL, Jacobs AH, Schlegel U, Heneka MT. Grommes C, et al. Mol Pharmacol. 2006 Nov;70(5):1524-33. doi: 10.1124/mol.106.022194. Epub 2006 Aug 3. Mol Pharmacol. 2006. PMID: 16887936
The nonthiazolidinedione tyrosine-based peroxisome proliferator-activated receptor gamma ligand GW7845 induces apoptosis and limits migration and invasion of rat and human glioma cells.
Grommes C, Landreth GE, Schlegel U, Heneka MT. Grommes C, et al. J Pharmacol Exp Ther. 2005 May;313(2):806-13. doi: 10.1124/jpet.104.078972. Epub 2005 Jan 21. J Pharmacol Exp Ther. 2005. PMID: 15665144
Induction of apoptosis in human and rat glioma by agonists of the nuclear receptor PPARgamma.
Zander T, Kraus JA, Grommes C, Schlegel U, Feinstein D, Klockgether T, Landreth G, Koenigsknecht J, Heneka MT. Zander T, et al. Among authors: grommes c. J Neurochem. 2002 Jun;81(5):1052-60. doi: 10.1046/j.1471-4159.2002.00899.x. J Neurochem. 2002. PMID: 12065618
The PPARĪ³ agonist pioglitazone crosses the blood-brain barrier and reduces tumor growth in a human xenograft model.
Grommes C, Karlo JC, Caprariello A, Blankenship D, Dechant A, Landreth GE. Grommes C, et al. Cancer Chemother Pharmacol. 2013 Apr;71(4):929-36. doi: 10.1007/s00280-013-2084-2. Epub 2013 Jan 29. Cancer Chemother Pharmacol. 2013. PMID: 23358645
Regulation of microglial phagocytosis and inflammatory gene expression by Gas6 acting on the Axl/Mer family of tyrosine kinases.
Grommes C, Lee CY, Wilkinson BL, Jiang Q, Koenigsknecht-Talboo JL, Varnum B, Landreth GE. Grommes C, et al. J Neuroimmune Pharmacol. 2008 Jun;3(2):130-40. doi: 10.1007/s11481-007-9090-2. Epub 2007 Oct 10. J Neuroimmune Pharmacol. 2008. PMID: 18247125 Free PMC article.
Fibrillar beta-amyloid-stimulated intracellular signaling cascades require Vav for induction of respiratory burst and phagocytosis in monocytes and microglia.
Wilkinson B, Koenigsknecht-Talboo J, Grommes C, Lee CY, Landreth G. Wilkinson B, et al. Among authors: grommes c. J Biol Chem. 2006 Jul 28;281(30):20842-50. doi: 10.1074/jbc.M600627200. Epub 2006 May 25. J Biol Chem. 2006. PMID: 16728400
Genomic Heterogeneity Underlies Mixed Response to Tropomyosin Receptor Kinase Inhibition in Recurrent Glioma.
Schram AM, Jonsson P, Drilon A, Bale TA, Hechtman JF, Benayed R, Hanusch B, Young RJ, Grommes C, Ku N, Kaley T, Hyman DM, Taylor BS. Schram AM, et al. Among authors: grommes c. JCO Precis Oncol. 2018;2:PO.18.00089. doi: 10.1200/PO.18.00089. Epub 2018 Aug 8. JCO Precis Oncol. 2018. PMID: 31218270 Free PMC article. No abstract available.
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