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219 results
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Crystal structure of the ligand-binding domain of the human nuclear receptor RXR-alpha.
Bourguet W, Ruff M, Chambon P, Gronemeyer H, Moras D. Bourguet W, et al. Among authors: gronemeyer h. Nature. 1995 Jun 1;375(6530):377-82. doi: 10.1038/375377a0. Nature. 1995. PMID: 7760929
RAR and RXR modulation in cancer and metabolic disease.
Altucci L, Leibowitz MD, Ogilvie KM, de Lera AR, Gronemeyer H. Altucci L, et al. Among authors: gronemeyer h. Nat Rev Drug Discov. 2007 Oct;6(10):793-810. doi: 10.1038/nrd2397. Nat Rev Drug Discov. 2007. PMID: 17906642 Review.
Dual RXR Agonists and RAR Antagonists Based on the Stilbene Retinoid Scaffold.
Martínez C, Lieb M, Alvarez S, Rodríguez-Barrios F, Alvarez R, Khanwalkar H, Gronemeyer H, de Lera AR. Martínez C, et al. Among authors: gronemeyer h. ACS Med Chem Lett. 2014 Mar 19;5(5):533-7. doi: 10.1021/ml400521f. eCollection 2014 May 8. ACS Med Chem Lett. 2014. PMID: 24900875 Free PMC article.
Modulation of RXR function through ligand design.
Pérez E, Bourguet W, Gronemeyer H, de Lera AR. Pérez E, et al. Among authors: gronemeyer h. Biochim Biophys Acta. 2012 Jan;1821(1):57-69. doi: 10.1016/j.bbalip.2011.04.003. Epub 2011 Apr 16. Biochim Biophys Acta. 2012. PMID: 21515403 Review.
Design of selective nuclear receptor modulators: RAR and RXR as a case study.
de Lera AR, Bourguet W, Altucci L, Gronemeyer H. de Lera AR, et al. Among authors: gronemeyer h. Nat Rev Drug Discov. 2007 Oct;6(10):811-20. doi: 10.1038/nrd2398. Nat Rev Drug Discov. 2007. PMID: 17906643 Review.
Structure, function and modulation of retinoic acid receptor beta, a tumor suppressor.
Alvarez S, Germain P, Alvarez R, Rodríguez-Barrios F, Gronemeyer H, de Lera AR. Alvarez S, et al. Among authors: gronemeyer h. Int J Biochem Cell Biol. 2007;39(7-8):1406-15. doi: 10.1016/j.biocel.2007.02.010. Epub 2007 Feb 22. Int J Biochem Cell Biol. 2007. PMID: 17433757 Review.
Critical role of retinoid/rexinoid signaling in mediating transformation and therapeutic response of NUP98-RARG leukemia.
Qiu JJ, Zeisig BB, Li S, Liu W, Chu H, Song Y, Giordano A, Schwaller J, Gronemeyer H, Dong S, So CW. Qiu JJ, et al. Among authors: gronemeyer h. Leukemia. 2015 May;29(5):1153-62. doi: 10.1038/leu.2014.334. Epub 2014 Dec 16. Leukemia. 2015. PMID: 25510432
Co-resistance to retinoic acid and TRAIL by insertion mutagenesis into RAM.
Yin W, Rossin A, Clifford JL, Gronemeyer H. Yin W, et al. Among authors: gronemeyer h. Oncogene. 2006 Jun 22;25(26):3735-44. doi: 10.1038/sj.onc.1209410. Epub 2006 Jan 30. Oncogene. 2006. PMID: 16449964
Molecular mechanisms of retinoid action.
Gronemeyer H, Miturski R. Gronemeyer H, et al. Cell Mol Biol Lett. 2001;6(1):3-52. Cell Mol Biol Lett. 2001. PMID: 11544629 Review.
Retinoic acid-induced apoptosis in leukemia cells is mediated by paracrine action of tumor-selective death ligand TRAIL.
Altucci L, Rossin A, Raffelsberger W, Reitmair A, Chomienne C, Gronemeyer H. Altucci L, et al. Among authors: gronemeyer h. Nat Med. 2001 Jun;7(6):680-6. doi: 10.1038/89050. Nat Med. 2001. PMID: 11385504
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