Grootendorst DC - Search Results

1

Selective phosphodiesterase inhibitors for the treatment of asthma and chronic obstructive pulmonary disease.

Grootendorst DC, Rabe KF. Grootendorst DC, et al. Curr Opin Allergy Clin Immunol. 2002 Feb;2(1):61-7. doi: 10.1097/00130832-200202000-00010. Curr Opin Allergy Clin Immunol. 2002. PMID: 11964752 Review.

2

Chronic sinusitis in severe asthma is related to sputum eosinophilia.

ten Brinke A, Grootendorst DC, Schmidt JT, De Bruïne FT, van Buchem MA, Sterk PJ, Rabe KF, Bel EH. ten Brinke A, et al. Among authors: grootendorst dc. J Allergy Clin Immunol. 2002 Apr;109(4):621-6. doi: 10.1067/mai.2002.122458. J Allergy Clin Immunol. 2002. PMID: 11941310

3

Antiinflammatory effects of the phosphodiesterase-4 inhibitor cilomilast (Ariflo) in chronic obstructive pulmonary disease.

Gamble E, Grootendorst DC, Brightling CE, Troy S, Qiu Y, Zhu J, Parker D, Matin D, Majumdar S, Vignola AM, Kroegel C, Morell F, Hansel TT, Rennard SI, Compton C, Amit O, Tat T, Edelson J, Pavord ID, Rabe KF, Barnes NC, Jeffery PK. Gamble E, et al. Among authors: grootendorst dc. Am J Respir Crit Care Med. 2003 Oct 15;168(8):976-82. doi: 10.1164/rccm.200212-1490OC. Epub 2003 Jun 19. Am J Respir Crit Care Med. 2003. PMID: 12816740 Clinical Trial.

4

Mechanisms of bronchial hyperreactivity in asthma and chronic obstructive pulmonary disease.

Grootendorst DC, Rabe KF. Grootendorst DC, et al. Proc Am Thorac Soc. 2004;1(2):77-87. doi: 10.1513/pats.2306025. Proc Am Thorac Soc. 2004. PMID: 16113417 Review.

5

Reduction in sputum neutrophil and eosinophil numbers by the PDE4 inhibitor roflumilast in patients with COPD.

Grootendorst DC, Gauw SA, Verhoosel RM, Sterk PJ, Hospers JJ, Bredenbröker D, Bethke TD, Hiemstra PS, Rabe KF. Grootendorst DC, et al. Thorax. 2007 Dec;62(12):1081-7. doi: 10.1136/thx.2006.075937. Epub 2007 Jun 15. Thorax. 2007. PMID: 17573446 Free PMC article. Clinical Trial.

6

Does a single dose of the phosphodiesterase 4 inhibitor, cilomilast (15 mg), induce bronchodilation in patients with chronic obstructive pulmonary disease?

Grootendorst DC, Gauw SA, Baan R, Kelly J, Murdoch RD, Sterk PJ, Rabe KF. Grootendorst DC, et al. Pulm Pharmacol Ther. 2003;16(2):115-20. doi: 10.1016/S1094-5539(02)00172-4. Pulm Pharmacol Ther. 2003. PMID: 12670781 Clinical Trial.

7

Efficacy of the novel phosphodiesterase-4 inhibitor BAY 19-8004 on lung function and airway inflammation in asthma and chronic obstructive pulmonary disease (COPD).

Grootendorst DC, Gauw SA, Benschop N, Sterk PJ, Hiemstra PS, Rabe KF. Grootendorst DC, et al. Pulm Pharmacol Ther. 2003;16(6):341-7. doi: 10.1016/S1094-5539(03)00090-7. Pulm Pharmacol Ther. 2003. PMID: 14580925 Clinical Trial.

8

Airway mucosal inflammation in COPD is similar in smokers and ex-smokers: a pooled analysis.

Gamble E, Grootendorst DC, Hattotuwa K, O'Shaughnessy T, Ram FS, Qiu Y, Zhu J, Vignola AM, Kroegel C, Morell F, Pavord ID, Rabe KF, Jeffery PK, Barnes NC. Gamble E, et al. Among authors: grootendorst dc. Eur Respir J. 2007 Sep;30(3):467-71. doi: 10.1183/09031936.00013006. Epub 2007 May 15. Eur Respir J. 2007. PMID: 17504799 Free article.

9

CD11b and L-selectin expression on eosinophils and neutrophils in blood and induced sputum of patients with asthma compared with normal subjects.

in 't Veen JC, Grootendorst DC, Bel EH, Smits HH, Van Der Keur M, Sterk PJ, Hiemstra PS. in 't Veen JC, et al. Among authors: grootendorst dc. Clin Exp Allergy. 1998 May;28(5):606-15. doi: 10.1046/j.1365-2222.1998.00279.x. Clin Exp Allergy. 1998. PMID: 9645598

10

Benefits of high altitude allergen avoidance in atopic adolescents with moderate to severe asthma, over and above treatment with high dose inhaled steroids.

Grootendorst DC, Dahlén SE, Van Den Bos JW, Duiverman EJ, Veselic-Charvat M, Vrijlandt EJ, O'Sullivan S, Kumlin M, Sterk PJ, Roldaan AC. Grootendorst DC, et al. Clin Exp Allergy. 2001 Mar;31(3):400-8. doi: 10.1046/j.1365-2222.2001.01022.x. Clin Exp Allergy. 2001. PMID: 11260151

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