Gros R - Search Results

1

Collagenase-resistant collagen promotes mouse aging and vascular cell senescence.

Vafaie F, Yin H, O'Neil C, Nong Z, Watson A, Arpino JM, Chu MW, Wayne Holdsworth D, Gros R, Pickering JG. Vafaie F, et al. Among authors: gros r. Aging Cell. 2014 Feb;13(1):121-30. doi: 10.1111/acel.12155. Epub 2013 Sep 19. Aging Cell. 2014. PMID: 23957394 Free PMC article.

2

The impact of blunted beta-adrenergic responsiveness on growth regulatory pathways in hypertension.

Gros R, Ding Q, Chorazyczewski J, Andrews J, Pickering JG, Hegele RA, Feldman RD. Gros R, et al. Mol Pharmacol. 2006 Jan;69(1):317-27. doi: 10.1124/mol.105.013953. Epub 2005 Oct 13. Mol Pharmacol. 2006. PMID: 16223959

3

Rapid effects of aldosterone on clonal human vascular smooth muscle cells.

Gros R, Ding Q, Armstrong S, O'Neil C, Pickering JG, Feldman RD. Gros R, et al. Am J Physiol Cell Physiol. 2007 Feb;292(2):C788-94. doi: 10.1152/ajpcell.00407.2006. Epub 2006 Sep 13. Am J Physiol Cell Physiol. 2007. PMID: 16971490 Free article.

4

Adenylyl cyclase isoform-selective regulation of vascular smooth muscle proliferation and cytoskeletal reorganization.

Gros R, Ding Q, Chorazyczewski J, Pickering JG, Limbird LE, Feldman RD. Gros R, et al. Circ Res. 2006 Oct 13;99(8):845-52. doi: 10.1161/01.RES.0000245189.21703.c0. Epub 2006 Sep 14. Circ Res. 2006. PMID: 16973907

5

Increased enzyme activity and beta-adrenergic mediated vasodilation in subjects expressing a single-nucleotide variant of human adenylyl cyclase 6.

Gros R, Van Uum S, Hutchinson-Jaffe A, Ding Q, Pickering JG, Hegele RA, Feldman RD. Gros R, et al. Arterioscler Thromb Vasc Biol. 2007 Dec;27(12):2657-63. doi: 10.1161/ATVBAHA.107.145557. Epub 2007 Oct 4. Arterioscler Thromb Vasc Biol. 2007. PMID: 17916776

6

Fibroblast growth factor 9 delivery during angiogenesis produces durable, vasoresponsive microvessels wrapped by smooth muscle cells.

Frontini MJ, Nong Z, Gros R, Drangova M, O'Neil C, Rahman MN, Akawi O, Yin H, Ellis CG, Pickering JG. Frontini MJ, et al. Among authors: gros r. Nat Biotechnol. 2011 May;29(5):421-7. doi: 10.1038/nbt.1845. Epub 2011 Apr 17. Nat Biotechnol. 2011. PMID: 21499246

7

Delineating the receptor mechanisms underlying the rapid vascular contractile effects of aldosterone and estradiol.

Gros R, Ding Q, Davis M, Shaikh R, Liu B, Chorazyczewski J, Pickering JG, Feldman RD. Gros R, et al. Can J Physiol Pharmacol. 2011 Sep;89(9):655-63. doi: 10.1139/y11-062. Epub 2011 Aug 19. Can J Physiol Pharmacol. 2011. PMID: 21854125

8

Type I collagen cleavage is essential for effective fibrotic repair after myocardial infarction.

Nong Z, O'Neil C, Lei M, Gros R, Watson A, Rizkalla A, Mequanint K, Li S, Frontini MJ, Feng Q, Pickering JG. Nong Z, et al. Among authors: gros r. Am J Pathol. 2011 Nov;179(5):2189-98. doi: 10.1016/j.ajpath.2011.07.017. Epub 2011 Sep 9. Am J Pathol. 2011. PMID: 21907695 Free PMC article.

9

Fibroblast Growth Factor 9 Imparts Hierarchy and Vasoreactivity to the Microcirculation of Renal Tumors and Suppresses Metastases.

Yin H, Frontini MJ, Arpino JM, Nong Z, O'Neil C, Xu Y, Balint B, Ward AD, Chakrabarti S, Ellis CG, Gros R, Pickering JG. Yin H, et al. Among authors: gros r. J Biol Chem. 2015 Sep 4;290(36):22127-42. doi: 10.1074/jbc.M115.652222. Epub 2015 Jul 16. J Biol Chem. 2015. PMID: 26183774 Free PMC article.

10

Aldosterone mediates metastatic spread of renal cancer via the G protein-coupled estrogen receptor (GPER).

Feldman RD, Ding Q, Hussain Y, Limbird LE, Pickering JG, Gros R. Feldman RD, et al. Among authors: gros r. FASEB J. 2016 Jun;30(6):2086-96. doi: 10.1096/fj.15-275552. Epub 2016 Feb 24. FASEB J. 2016. PMID: 26911792

Taken together, these findings provide strong evidence for aldosterone serving a causal role in renal cell cancer regulation via its GPER receptor; thus, antagonism of GPER represents a potential new target for treatment to reduce metastatic spread.-Feldman, R. D., Ding, Q …

Taken together, these findings provide strong evidence for aldosterone serving a causal role in renal cell cancer regulation via its GPER re …

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