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Analysis of the therapeutic efficacy of different doses of budesonide in patients with active Crohn's ileocolitis depending on disease activity and localization.
Herfarth H, Gross V, Andus T, Caesar I, Vogelsang H, Adler G, Malchow H, Petri A, Gierend M, Schölmerich J; German/Austrian Budesonide Study Group. Herfarth H, et al. Among authors: Gross V. Int J Colorectal Dis. 2004 Mar;19(2):147-52. doi: 10.1007/s00384-003-0529-5. Epub 2003 Sep 9. Int J Colorectal Dis. 2004. PMID: 13680283 Clinical Trial.
Strictures in Crohn's disease are characterised by an accumulation of mast cells colocalised with laminin but not with fibronectin or vitronectin.
Gelbmann CM, Mestermann S, Gross V, Köllinger M, Schölmerich J, Falk W. Gelbmann CM, et al. Among authors: Gross V. Gut. 1999 Aug;45(2):210-7. doi: 10.1136/gut.45.2.210. Gut. 1999. PMID: 10403732 Free PMC article.
RESULTS: In strictures in Crohn's disease, a striking accumulation of mast cells was seen particularly in the hypertrophied and fibrotic muscularis propria, with a mean (SEM) mast cell number of 81.3 (14.9) v 1.5 (0.9)/mm(2) in normal bowel (p<0.0005). ...
RESULTS: In strictures in Crohn's disease, a striking accumulation of mast cells was seen particularly in the hypertrophied and fibrotic mus …
Glucocorticoid receptors are down-regulated in inflamed colonic mucosa but not in peripheral blood mononuclear cells from patients with inflammatory bowel disease.
Rogler G, Meinel A, Lingauer A, Michl J, Zietz B, Gross V, Lang B, Andus T, Schölmerich J, Palitzsch KD. Rogler G, et al. Among authors: Gross V. Eur J Clin Invest. 1999 Apr;29(4):330-6. doi: 10.1046/j.1365-2362.1999.00460.x. Eur J Clin Invest. 1999. PMID: 10231345
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