Grosse S - Search Results

1

A Robust and All-Inclusive Pipeline for Shuffling of Adeno-Associated Viruses.

Herrmann AK, Bender C, Kienle E, Grosse S, El Andari J, Botta J, Schürmann N, Wiedtke E, Niopek D, Grimm D. Herrmann AK, et al. Among authors: grosse s. ACS Synth Biol. 2019 Jan 18;8(1):194-206. doi: 10.1021/acssynbio.8b00373. Epub 2019 Jan 8. ACS Synth Biol. 2019. PMID: 30513195

2

Engineering and evolution of synthetic adeno-associated virus (AAV) gene therapy vectors via DNA family shuffling.

Kienle E, Senís E, Börner K, Niopek D, Wiedtke E, Grosse S, Grimm D. Kienle E, et al. Among authors: grosse s. J Vis Exp. 2012 Apr 2;(62):3819. doi: 10.3791/3819. J Vis Exp. 2012. PMID: 22491297 Free PMC article.

3

CRISPR/Cas9-mediated genome engineering: an adeno-associated viral (AAV) vector toolbox.

Senís E, Fatouros C, Große S, Wiedtke E, Niopek D, Mueller AK, Börner K, Grimm D. Senís E, et al. Among authors: grosse s. Biotechnol J. 2014 Nov;9(11):1402-12. doi: 10.1002/biot.201400046. Epub 2014 Oct 6. Biotechnol J. 2014. PMID: 25186301

4

Relevance of Assembly-Activating Protein for Adeno-associated Virus Vector Production and Capsid Protein Stability in Mammalian and Insect Cells.

Grosse S, Penaud-Budloo M, Herrmann AK, Börner K, Fakhiri J, Laketa V, Krämer C, Wiedtke E, Gunkel M, Ménard L, Ayuso E, Grimm D. Grosse S, et al. J Virol. 2017 Sep 27;91(20):e01198-17. doi: 10.1128/JVI.01198-17. Print 2017 Oct 15. J Virol. 2017. PMID: 28768875 Free PMC article.

5

Impact of the Assembly-Activating Protein on Molecular Evolution of Synthetic Adeno-Associated Virus Capsids.

Herrmann AK, Große S, Börner K, Krämer C, Wiedtke E, Gunkel M, Grimm D. Herrmann AK, et al. Among authors: grosse s. Hum Gene Ther. 2019 Jan;30(1):21-35. doi: 10.1089/hum.2018.085. Epub 2018 Dec 18. Hum Gene Ther. 2019. PMID: 29978729

6

Alleviation of off-target effects from vector-encoded shRNAs via codelivered RNA decoys.

Mockenhaupt S, Grosse S, Rupp D, Bartenschlager R, Grimm D. Mockenhaupt S, et al. Among authors: grosse s. Proc Natl Acad Sci U S A. 2015 Jul 28;112(30):E4007-16. doi: 10.1073/pnas.1510476112. Epub 2015 Jul 13. Proc Natl Acad Sci U S A. 2015. PMID: 26170322 Free PMC article.

7

Blocking sense-strand activity improves potency, safety and specificity of anti-hepatitis B virus short hairpin RNA.

Michler T, Große S, Mockenhaupt S, Röder N, Stückler F, Knapp B, Ko C, Heikenwalder M, Protzer U, Grimm D. Michler T, et al. Among authors: grosse s. EMBO Mol Med. 2016 Sep 1;8(9):1082-98. doi: 10.15252/emmm.201506172. Print 2016 Sep. EMBO Mol Med. 2016. PMID: 27473329 Free PMC article.

8

Cell-specific CRISPR-Cas9 activation by microRNA-dependent expression of anti-CRISPR proteins.

Hoffmann MD, Aschenbrenner S, Grosse S, Rapti K, Domenger C, Fakhiri J, Mastel M, Börner K, Eils R, Grimm D, Niopek D. Hoffmann MD, et al. Among authors: grosse s. Nucleic Acids Res. 2019 Jul 26;47(13):e75. doi: 10.1093/nar/gkz271. Nucleic Acids Res. 2019. PMID: 30982889 Free PMC article.

9

TALEN/CRISPR-mediated engineering of a promoterless anti-viral RNAi hairpin into an endogenous miRNA locus.

Senís E, Mockenhaupt S, Rupp D, Bauer T, Paramasivam N, Knapp B, Gronych J, Grosse S, Windisch MP, Schmidt F, Theis FJ, Eils R, Lichter P, Schlesner M, Bartenschlager R, Grimm D. Senís E, et al. Among authors: grosse s. Nucleic Acids Res. 2017 Jan 9;45(1):e3. doi: 10.1093/nar/gkw805. Epub 2016 Sep 9. Nucleic Acids Res. 2017. PMID: 27614072 Free PMC article.

10

Death receptor-based enrichment of Cas9-expressing cells.

Liesche C, Venkatraman L, Aschenbrenner S, Grosse S, Grimm D, Eils R, Beaudouin J. Liesche C, et al. Among authors: grosse s. BMC Biotechnol. 2016 Feb 16;16:17. doi: 10.1186/s12896-016-0250-4. BMC Biotechnol. 2016. PMID: 26883910 Free PMC article.

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