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Sensory irritation to mixtures of formaldehyde, acrolein, and acetaldehyde in rats.
Cassee FR, Arts JH, Groten JP, Feron VJ. Cassee FR, et al. Among authors: groten jp. Arch Toxicol. 1996;70(6):329-37. doi: 10.1007/s002040050282. Arch Toxicol. 1996. PMID: 8975631
Toxicogenomics concepts and applications to study hepatic effects of food additives and chemicals.
Stierum R, Heijne W, Kienhuis A, van Ommen B, Groten J. Stierum R, et al. Toxicol Appl Pharmacol. 2005 Sep 1;207(2 Suppl):179-88. doi: 10.1016/j.taap.2005.01.050. Toxicol Appl Pharmacol. 2005. PMID: 16139318 Review.
Transcriptome analysis provides new insights into liver changes induced in the rat upon dietary administration of the food additives butylated hydroxytoluene, curcumin, propyl gallate and thiabendazole.
Stierum R, Conesa A, Heijne W, Ommen Bv, Junker K, Scott MP, Price RJ, Meredith C, Lake BG, Groten J. Stierum R, et al. Food Chem Toxicol. 2008 Aug;46(8):2616-28. doi: 10.1016/j.fct.2008.04.019. Epub 2008 Apr 25. Food Chem Toxicol. 2008. PMID: 18539377
Toxicogenomic analysis of gene expression changes in rat liver after a 28-day oral benzene exposure.
Heijne WH, Jonker D, Stierum RH, van Ommen B, Groten JP. Heijne WH, et al. Among authors: groten jp. Mutat Res. 2005 Aug 4;575(1-2):85-101. doi: 10.1016/j.mrfmmm.2005.02.003. Mutat Res. 2005. PMID: 15878777
International issues on human health effects of exposure to chemical mixtures.
Feron VJ, Cassee FR, Groten JP, van Vliet PW, van Zorge JA. Feron VJ, et al. Among authors: groten jp. Environ Health Perspect. 2002 Dec;110 Suppl 6(Suppl 6):893-9. doi: 10.1289/ehp.02110s6893. Environ Health Perspect. 2002. PMID: 12634116 Free PMC article. Review.
Bromobenzene-induced hepatotoxicity at the transcriptome level.
Heijne WH, Slitt AL, van Bladeren PJ, Groten JP, Klaassen CD, Stierum RH, van Ommen B. Heijne WH, et al. Among authors: groten jp. Toxicol Sci. 2004 Jun;79(2):411-22. doi: 10.1093/toxsci/kfh128. Epub 2004 Mar 31. Toxicol Sci. 2004. PMID: 15056800
Transcriptomics analysis of interactive effects of benzene, trichloroethylene and methyl mercury within binary and ternary mixtures on the liver and kidney following subchronic exposure in the rat.
Hendriksen PJ, Freidig AP, Jonker D, Thissen U, Bogaards JJ, Mumtaz MM, Groten JP, Stierum RH. Hendriksen PJ, et al. Among authors: groten jp. Toxicol Appl Pharmacol. 2007 Dec 1;225(2):171-88. doi: 10.1016/j.taap.2007.08.017. Epub 2007 Aug 29. Toxicol Appl Pharmacol. 2007. PMID: 17905399
Profiles of metabolites and gene expression in rats with chemically induced hepatic necrosis.
Heijne WH, Lamers RJ, van Bladeren PJ, Groten JP, van Nesselrooij JH, van Ommen B. Heijne WH, et al. Among authors: groten jp. Toxicol Pathol. 2005;33(4):425-33. doi: 10.1080/01926230590958146. Toxicol Pathol. 2005. PMID: 16036859
Effects of flavonoid mixtures on the transport of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) through Caco-2 monolayers: an in vitro and kinetic modeling approach to predict the combined effects on transporter inhibition.
Schutte ME, Boersma MG, Verhallen DA, Groten JP, Rietjens IM. Schutte ME, et al. Among authors: groten jp. Food Chem Toxicol. 2008 Feb;46(2):557-66. doi: 10.1016/j.fct.2007.08.038. Epub 2007 Sep 5. Food Chem Toxicol. 2008. PMID: 17935851
Toxicology of chemical mixtures: a challenging quest along empirical sciences.
Groten JP, Heijne WH, Stierum RH, Freidig AP, Feron VJ. Groten JP, et al. Environ Toxicol Pharmacol. 2004 Dec;18(3):185-92. doi: 10.1016/j.etap.2004.07.005. Environ Toxicol Pharmacol. 2004. PMID: 21782748
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