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2000 250
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7,315 results

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Page 1
Efficacy, safety, quality of life, adherence and cost-effectiveness of long-acting growth hormone replacement therapy compared to daily growth hormone in children with growth hormone deficiency: A systematic review and meta-analysis.
Mameli C, Orso M, Calcaterra V, Wasniewska MG, Aversa T, Granato S, Bruschini P, Guadagni L, d'Angela D, Spandonaro F, Polistena B, Zuccotti G. Mameli C, et al. Pharmacol Res. 2023 Jul;193:106805. doi: 10.1016/j.phrs.2023.106805. Epub 2023 May 24. Pharmacol Res. 2023. PMID: 37236413 Free article. Review.
We evaluated the efficacy, safety, adherence, quality of life (QoL) and cost-effectiveness of long-acting growth hormone (LAGH) vs daily growth hormone (GH) preparations in the treatment of growth hormone deficiency (GHD) in children. ...
We evaluated the efficacy, safety, adherence, quality of life (QoL) and cost-effectiveness of long-acting growth hormone (LAGH …
Growth hormone deficiency and replacement therapy in adults: Impact on survival.
van Bunderen CC, Olsson DS. van Bunderen CC, et al. Rev Endocr Metab Disord. 2021 Mar;22(1):125-133. doi: 10.1007/s11154-020-09599-w. Epub 2020 Oct 17. Rev Endocr Metab Disord. 2021. PMID: 33068227 Free PMC article. Review.
In a seminal paper from 1990, Rosen and Bengtsson suggested that hypopituitary patients with a presumed growth hormone (GH) deficiency (GHD) have an excess mortality. Later studies have confirmed this finding but have also shown that the cause of the increased risk …
In a seminal paper from 1990, Rosen and Bengtsson suggested that hypopituitary patients with a presumed growth hormone (GH) de …
Effects of adult growth hormone deficiency and replacement therapy on the cardiometabolic risk profile.
Ratku B, Sebestyén V, Erdei A, Nagy EV, Szabó Z, Somodi S. Ratku B, et al. Pituitary. 2022 Apr;25(2):211-228. doi: 10.1007/s11102-022-01207-1. Epub 2022 Feb 1. Pituitary. 2022. PMID: 35106704 Free PMC article. Review.
Adult growth hormone deficiency (AGHD) is considered a rare endocrine disorder involving patients with childhood-onset and adult-onset growth hormone deficiency (AoGHD) and characterized by adverse cardiometabolic risk profile. Besides traditional card …
Adult growth hormone deficiency (AGHD) is considered a rare endocrine disorder involving patients with childhood-onset and adu …
Growth Hormone Deficiency and Growth Hormone Replacement in Childhood Cancer Survivors.
Patterson BC, Meacham LR. Patterson BC, et al. Front Horm Res. 2021;54:25-35. doi: 10.1159/000515111. Epub 2021 Apr 30. Front Horm Res. 2021. PMID: 33934095 Review.
Growth hormone deficiency (GHD) is common in childhood cancer survivors (CCS). Major risk factors for GHD include radiation therapy, both cranial and total body irradiation, and tumor location. Some newer anti-cancer therapies may impact growth and the GH-IGF …
Growth hormone deficiency (GHD) is common in childhood cancer survivors (CCS). Major risk factors for GHD include radiation th …
Growth Hormone Treatment for Non-GHD Disorders: Excitement Tempered by Biology.
Grimberg A, Hawkes CP. Grimberg A, et al. J Clin Endocrinol Metab. 2024 Jan 18;109(2):e442-e454. doi: 10.1210/clinem/dgad417. J Clin Endocrinol Metab. 2024. PMID: 37450564 Free PMC article. Review.
The success of growth hormone (GH) replacement in children with classical GH deficiency has led to excitement that other causes of short stature may benefit similarly. However, clinical experience has shown less consistent and generally less dramatic effects …
The success of growth hormone (GH) replacement in children with classical GH deficiency has led to excitement that othe …
The physiology of growth hormone (GH) in adults: translational journey to GH replacement therapy.
Ho KK, O'Sullivan AJ, Burt MG. Ho KK, et al. J Endocrinol. 2023 Mar 30;257(2):e220197. doi: 10.1530/JOE-22-0197. Print 2023 May 1. J Endocrinol. 2023. PMID: 36524723 Review.
The fact that growth hormone (GH) plays an important role in health after the cessation of growth requiring replacement therapy in adult life has only been recognised in the last three decades. ...These pleiotropic actions explain the clinical picture …
The fact that growth hormone (GH) plays an important role in health after the cessation of growth requiring replacem …
Growth in girls with Turner syndrome.
Isojima T, Yokoya S. Isojima T, et al. Front Endocrinol (Lausanne). 2023 Jan 12;13:1068128. doi: 10.3389/fendo.2022.1068128. eCollection 2022. Front Endocrinol (Lausanne). 2023. PMID: 36714599 Free PMC article. Review.
Growth hormone (GH) has been used to accelerate growth and is known to increase adult height. ...In this review, we discuss the growth in girls with TS, including overall growth, pubertal growth, the secular trend, growth-promoting …
Growth hormone (GH) has been used to accelerate growth and is known to increase adult height. ...In this review, we dis …
Developments in the Management of Growth Hormone Deficiency: Clinical Utility of Somapacitan.
Miller BS, Blair J, Horikawa R, Linglart A, Yuen KCJ. Miller BS, et al. Drug Des Devel Ther. 2024 Feb 3;18:291-306. doi: 10.2147/DDDT.S315172. eCollection 2024. Drug Des Devel Ther. 2024. PMID: 38333899 Free PMC article. Review.
Growth hormone (GH) replacement therapy for growth hormone deficiency (GHD) in children and adults has for over 25 years, until recently, been administered as daily injections. ...To address this shortcoming, long-acting growth hormones ( …
Growth hormone (GH) replacement therapy for growth hormone deficiency (GHD) in children and adults has fo …
Is there a role for growth hormone replacement in adults to control acute and post-acute COVID-19?
Venugopal N, Armstrong PA, Wright TJ, Randolph KM, Batson RD, Yuen KCJ, Masel B, Sheffield-Moore M, Pyles RB, Urban RJ. Venugopal N, et al. Best Pract Res Clin Endocrinol Metab. 2023 Dec;37(6):101842. doi: 10.1016/j.beem.2023.101842. Epub 2023 Nov 19. Best Pract Res Clin Endocrinol Metab. 2023. PMID: 37996257 Review.
Mounting evidence suggests these extrapulmonary manifestations may ultimately lead to reduced growth hormone (GH) secretion as demonstrated following stimulation tests. Disrupted GH secretion could cause or exacerbate long lasting neuropsychological symptoms as seen …
Mounting evidence suggests these extrapulmonary manifestations may ultimately lead to reduced growth hormone (GH) secretion as …
Long-acting growth hormone in the treatment of growth hormone deficiency in children: a systematic literature review and network meta-analysis.
Zhu J, Yuan K, Rana S, Jakki SL, Bhat AS, Liang L, Wang C. Zhu J, et al. Sci Rep. 2024 Apr 5;14(1):8061. doi: 10.1038/s41598-024-58616-4. Sci Rep. 2024. PMID: 38580693 Free PMC article.
The purpose of this study is to compare the relative efficacy and safety of long-acting growth hormone (LAGH) as a growth hormone replacement therapy in prepubertal children with growth hormone deficiency (GHD). ...PEG-LAGH showed …
The purpose of this study is to compare the relative efficacy and safety of long-acting growth hormone (LAGH) as a growth …
7,315 results