Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

My NCBI Filters
Text availability
Article attribute
Article type
Publication date

Search Results

204 results
Filters applied: . Clear all Results are displayed in a computed author sort order. Results by year timeline is unavailable
Page 1
The epigenetics of rRNA genes: from molecular to chromosome biology.
McStay B, Grummt I. McStay B, et al. Annu Rev Cell Dev Biol. 2008;24:131-57. doi: 10.1146/annurev.cellbio.24.110707.175259. Annu Rev Cell Dev Biol. 2008. PMID: 18616426 Review.
We also review the critical role of the RNA polymerase I transcription factor UBF in the formation of active nucleolar organizer regions (NORs) and maintenance of the euchromatic state of rRNA genes....
We also review the critical role of the RNA polymerase I transcription factor UBF in the formation of active nucleolar organizer regi …
Epigenetic disruption of ribosomal RNA genes and nucleolar architecture in DNA methyltransferase 1 (Dnmt1) deficient cells.
Espada J, Ballestar E, Santoro R, Fraga MF, Villar-Garea A, Németh A, Lopez-Serra L, Ropero S, Aranda A, Orozco H, Moreno V, Juarranz A, Stockert JC, Längst G, Grummt I, Bickmore W, Esteller M. Espada J, et al. Nucleic Acids Res. 2007;35(7):2191-8. doi: 10.1093/nar/gkm118. Epub 2007 Mar 13. Nucleic Acids Res. 2007. PMID: 17355984 Free PMC article.
Dynamic regulation of nucleolar architecture.
Németh A, Grummt I. Németh A, et al. Curr Opin Cell Biol. 2018 Jun;52:105-111. doi: 10.1016/j.ceb.2018.02.013. Epub 2018 Mar 9. Curr Opin Cell Biol. 2018. PMID: 29529563 Review.
Different epigenetic layers engage in complex crosstalk to define the epigenetic state of mammalian rRNA genes.
Grummt I. Grummt I. Hum Mol Genet. 2007 Apr 15;16 Spec No 1:R21-7. doi: 10.1093/hmg/ddm020. Hum Mol Genet. 2007. PMID: 17613545 Review.
The presence of two epigenetically distinct states of rRNA genes provides a unique opportunity to decipher the molecular mechanisms that establish the euchromatic, i.e. transcriptionally active, and the heterochromatic, i.e. transcriptionally silent, state of rDNA. …
The presence of two epigenetically distinct states of rRNA genes provides a unique opportunity to decipher the molecular mechanisms that est …
The chromatin remodeling complex NuRD establishes the poised state of rRNA genes characterized by bivalent histone modifications and altered nucleosome positions.
Xie W, Ling T, Zhou Y, Feng W, Zhu Q, Stunnenberg HG, Grummt I, Tao W. Xie W, et al. Proc Natl Acad Sci U S A. 2012 May 22;109(21):8161-6. doi: 10.1073/pnas.1201262109. Epub 2012 May 8. Proc Natl Acad Sci U S A. 2012. PMID: 22570494 Free PMC article.
TAF12 recruits Gadd45a and the nucleotide excision repair complex to the promoter of rRNA genes leading to active DNA demethylation.
Schmitz KM, Schmitt N, Hoffmann-Rohrer U, Schäfer A, Grummt I, Mayer C. Schmitz KM, et al. Mol Cell. 2009 Feb 13;33(3):344-53. doi: 10.1016/j.molcel.2009.01.015. Mol Cell. 2009. PMID: 19217408
Demethylation of rDNA is initiated by recruitment of Gadd45a (growth arrest and DNA damage inducible protein 45 alpha) to the rDNA promoter by TAF12, a TBP-associated factor that is contained in Pol I- and Pol II-specific TBP-TAF complexes. ...
Demethylation of rDNA is initiated by recruitment of Gadd45a (growth arrest and DNA damage inducible protein 45 alpha) to the rDNA promoter …
Quiescence-induced LncRNAs trigger H4K20 trimethylation and transcriptional silencing.
Bierhoff H, Dammert MA, Brocks D, Dambacher S, Schotta G, Grummt I. Bierhoff H, et al. Mol Cell. 2014 May 22;54(4):675-82. doi: 10.1016/j.molcel.2014.03.032. Epub 2014 Apr 24. Mol Cell. 2014. PMID: 24768537
Interaction of noncoding RNA with the rDNA promoter mediates recruitment of DNMT3b and silencing of rRNA genes.
Schmitz KM, Mayer C, Postepska A, Grummt I. Schmitz KM, et al. Genes Dev. 2010 Oct 15;24(20):2264-9. doi: 10.1101/gad.590910. Genes Dev. 2010. PMID: 20952535 Free PMC article.
We show that pRNA interacts with the target site of the transcription factor TTF-I, forming a DNA:RNA triplex that is specifically recognized by the DNA methyltransferase DNMT3b. ...
We show that pRNA interacts with the target site of the transcription factor TTF-I, forming a DNA:RNA triplex that is specifically re …
DNA sequence encoded repression of rRNA gene transcription in chromatin.
Felle M, Exler JH, Merkl R, Dachauer K, Brehm A, Grummt I, Längst G. Felle M, et al. Nucleic Acids Res. 2010 Sep;38(16):5304-14. doi: 10.1093/nar/gkq263. Epub 2010 Apr 25. Nucleic Acids Res. 2010. PMID: 20421213 Free PMC article.
We suggest that nucleosome remodelling precedes promoter-dependent transcriptional activation as specific inhibition of ATP-dependent chromatin remodelling suppresses the initiation of RNA Polymerase I transcription in vitro. Once initiated, RNA Polymerase I is capa …
We suggest that nucleosome remodelling precedes promoter-dependent transcriptional activation as specific inhibition of ATP-dependent chroma …
204 results
Jump to page
Feedback