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GTP hydrolysis by Ran is required for nuclear envelope assembly.
Hetzer M, Bilbao-Cortés D, Walther TC, Gruss OJ, Mattaj IW. Hetzer M, et al. Mol Cell. 2000 Jun;5(6):1013-24. doi: 10.1016/s1097-2765(00)80266-x. Mol Cell. 2000. PMID: 10911995
Human TPX2 is required for targeting Aurora-A kinase to the spindle.
Kufer TA, Silljé HH, Körner R, Gruss OJ, Meraldi P, Nigg EA. Kufer TA, et al. J Cell Biol. 2002 Aug 19;158(4):617-23. doi: 10.1083/jcb.200204155. Epub 2002 Aug 12. J Cell Biol. 2002. PMID: 12177045 Free PMC article.
Importin alpha-regulated nucleation of microtubules by TPX2.
Schatz CA, Santarella R, Hoenger A, Karsenti E, Mattaj IW, Gruss OJ, Carazo-Salas RE. Schatz CA, et al. EMBO J. 2003 May 1;22(9):2060-70. doi: 10.1093/emboj/cdg195. EMBO J. 2003. PMID: 12727873 Free PMC article.
The mechanism of spindle assembly: functions of Ran and its target TPX2.
Gruss OJ, Vernos I. Gruss OJ, et al. J Cell Biol. 2004 Sep 27;166(7):949-55. doi: 10.1083/jcb.200312112. J Cell Biol. 2004. PMID: 15452138 Free PMC article. Review.
A centriole- and RanGTP-independent spindle assembly pathway in meiosis I of vertebrate oocytes.
Dumont J, Petri S, Pellegrin F, Terret ME, Bohnsack MT, Rassinier P, Georget V, Kalab P, Gruss OJ, Verlhac MH. Dumont J, et al. J Cell Biol. 2007 Jan 29;176(3):295-305. doi: 10.1083/jcb.200605199. J Cell Biol. 2007. PMID: 17261848 Free PMC article.
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