Gryaznov S - Search Results

1

Effects of a novel telomerase inhibitor, GRN163L, in human breast cancer.

Gellert GC, Dikmen ZG, Wright WE, Gryaznov S, Shay JW. Gellert GC, et al. Among authors: gryaznov s. Breast Cancer Res Treat. 2006 Mar;96(1):73-81. doi: 10.1007/s10549-005-9043-5. Epub 2005 Dec 1. Breast Cancer Res Treat. 2006. PMID: 16319992

2

A novel telomerase substrate precursor rapidly induces telomere dysfunction in telomerase positive cancer cells but not telomerase silent normal cells.

Mender I, Gryaznov S, Shay JW. Mender I, et al. Among authors: gryaznov s. Oncoscience. 2015 Aug 22;2(8):693-5. doi: 10.18632/oncoscience.213. eCollection 2015. Oncoscience. 2015. PMID: 26425659 Free PMC article.

3

Telomere maintenance in laser capture microdissection-purified Barrett's adenocarcinoma cells and effect of telomerase inhibition in vivo.

Shammas MA, Qazi A, Batchu RB, Bertheau RC, Wong JY, Rao MY, Prasad M, Chanda D, Ponnazhagan S, Anderson KC, Steffes CP, Munshi NC, De Vivo I, Beer DG, Gryaznov S, Weaver DW, Goyal RK. Shammas MA, et al. Among authors: gryaznov s. Clin Cancer Res. 2008 Aug 1;14(15):4971-80. doi: 10.1158/1078-0432.CCR-08-0473. Clin Cancer Res. 2008. PMID: 18676772 Free PMC article.

4

Induction of telomere dysfunction mediated by the telomerase substrate precursor 6-thio-2'-deoxyguanosine.

Mender I, Gryaznov S, Dikmen ZG, Wright WE, Shay JW. Mender I, et al. Among authors: gryaznov s. Cancer Discov. 2015 Jan;5(1):82-95. doi: 10.1158/2159-8290.CD-14-0609. Epub 2014 Dec 16. Cancer Discov. 2015. PMID: 25516420 Free PMC article.

5

Imetelstat (a telomerase antagonist) exerts off‑target effects on the cytoskeleton.

Mender I, Senturk S, Ozgunes N, Akcali KC, Kletsas D, Gryaznov S, Can A, Shay JW, Dikmen ZG. Mender I, et al. Among authors: gryaznov s. Int J Oncol. 2013 May;42(5):1709-15. doi: 10.3892/ijo.2013.1865. Epub 2013 Mar 27. Int J Oncol. 2013. PMID: 23545855 Free PMC article.

6

Telomerase antagonist imetelstat inhibits esophageal cancer cell growth and increases radiation-induced DNA breaks.

Wu X, Smavadati S, Nordfjäll K, Karlsson K, Qvarnström F, Simonsson M, Bergqvist M, Gryaznov S, Ekman S, Paulsson-Karlsson Y. Wu X, et al. Among authors: gryaznov s. Biochim Biophys Acta. 2012 Dec;1823(12):2130-5. doi: 10.1016/j.bbamcr.2012.08.003. Epub 2012 Aug 11. Biochim Biophys Acta. 2012. PMID: 22906540

7

In vivo inhibition of lung cancer by GRN163L: a novel human telomerase inhibitor.

Dikmen ZG, Gellert GC, Jackson S, Gryaznov S, Tressler R, Dogan P, Wright WE, Shay JW. Dikmen ZG, et al. Among authors: gryaznov s. Cancer Res. 2005 Sep 1;65(17):7866-73. doi: 10.1158/0008-5472.CAN-05-1215. Cancer Res. 2005. PMID: 16140956

8

Telomerase antagonists GRN163 and GRN163L inhibit tumor growth and increase chemosensitivity of human hepatoma.

Djojosubroto MW, Chin AC, Go N, Schaetzlein S, Manns MP, Gryaznov S, Harley CB, Rudolph KL. Djojosubroto MW, et al. Among authors: gryaznov s. Hepatology. 2005 Nov;42(5):1127-36. doi: 10.1002/hep.20822. Hepatology. 2005. PMID: 16114043

9

Effects of oligonucleotide N3'-->P5' thio-phosphoramidate (GRN163) targeting telomerase RNA in human multiple myeloma cells.

Akiyama M, Hideshima T, Shammas MA, Hayashi T, Hamasaki M, Tai YT, Richardson P, Gryaznov S, Munshi NC, Anderson KC. Akiyama M, et al. Among authors: gryaznov s. Cancer Res. 2003 Oct 1;63(19):6187-94. Cancer Res. 2003. PMID: 14559802

10

A novel telomerase template antagonist (GRN163) as a potential anticancer agent.

Asai A, Oshima Y, Yamamoto Y, Uochi TA, Kusaka H, Akinaga S, Yamashita Y, Pongracz K, Pruzan R, Wunder E, Piatyszek M, Li S, Chin AC, Harley CB, Gryaznov S. Asai A, et al. Among authors: gryaznov s. Cancer Res. 2003 Jul 15;63(14):3931-9. Cancer Res. 2003. PMID: 12873987

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