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A new role for the P2X7 receptor: a scavenger receptor for bacteria and apoptotic cells in the absence of serum and extracellular ATP.
Wiley JS, Gu BJ. Wiley JS, et al. Among authors: gu bj. Purinergic Signal. 2012 Sep;8(3):579-86. doi: 10.1007/s11302-012-9308-5. Epub 2012 Apr 4. Purinergic Signal. 2012. PMID: 22476940 Free PMC article. Review.
Point mutations confer loss of ATP-induced human P2X(7) receptor function.
Worthington RA, Smart ML, Gu BJ, Williams DA, Petrou S, Wiley JS, Barden JA. Worthington RA, et al. Among authors: gu bj. FEBS Lett. 2002 Feb 13;512(1-3):43-6. doi: 10.1016/s0014-5793(01)03311-7. FEBS Lett. 2002. PMID: 11852049
A loss-of-function polymorphic mutation in the cytolytic P2X7 receptor gene and chronic lymphocytic leukaemia: a molecular study.
Wiley JS, Dao-Ung LP, Gu BJ, Sluyter R, Shemon AN, Li C, Taper J, Gallo J, Manoharan A. Wiley JS, et al. Among authors: gu bj. Lancet. 2002 Mar 30;359(9312):1114-9. doi: 10.1016/S0140-6736(02)08156-4. Lancet. 2002. PMID: 11943260
P2X7 receptor cell surface expression and cytolytic pore formation are regulated by a distal C-terminal region.
Smart ML, Gu B, Panchal RG, Wiley J, Cromer B, Williams DA, Petrou S. Smart ML, et al. J Biol Chem. 2003 Mar 7;278(10):8853-60. doi: 10.1074/jbc.M211094200. Epub 2002 Dec 20. J Biol Chem. 2003. PMID: 12496266
An Ile-568 to Asn polymorphism prevents normal trafficking and function of the human P2X7 receptor.
Wiley JS, Dao-Ung LP, Li C, Shemon AN, Gu BJ, Smart ML, Fuller SJ, Barden JA, Petrou S, Sluyter R. Wiley JS, et al. Among authors: gu bj. J Biol Chem. 2003 May 9;278(19):17108-13. doi: 10.1074/jbc.M212759200. Epub 2003 Feb 13. J Biol Chem. 2003. PMID: 12586825
Specific detection of non-functional human P2X(7) receptors in HEK293 cells and B-lymphocytes.
Barden JA, Sluyter R, Gu BJ, Wiley JS. Barden JA, et al. Among authors: gu bj. FEBS Lett. 2003 Mar 13;538(1-3):159-62. doi: 10.1016/s0014-5793(03)00172-8. FEBS Lett. 2003. PMID: 12633871
An Arg307 to Gln polymorphism within the ATP-binding site causes loss of function of the human P2X7 receptor.
Gu BJ, Sluyter R, Skarratt KK, Shemon AN, Dao-Ung LP, Fuller SJ, Barden JA, Clarke AL, Petrou S, Wiley JS. Gu BJ, et al. J Biol Chem. 2004 Jul 23;279(30):31287-95. doi: 10.1074/jbc.M313902200. Epub 2004 Apr 27. J Biol Chem. 2004. PMID: 15123679
Rapid ATP-induced release of matrix metalloproteinase 9 is mediated by the P2X7 receptor.
Gu BJ, Wiley JS. Gu BJ, et al. Blood. 2006 Jun 15;107(12):4946-53. doi: 10.1182/blood-2005-07-2994. Epub 2006 Mar 2. Blood. 2006. PMID: 16514055
A quantitative method for routine measurement of cell surface P2X7 receptor function in leucocyte subsets by two-colour time-resolved flow cytometry.
Jursik C, Sluyter R, Georgiou JG, Fuller SJ, Wiley JS, Gu BJ. Jursik C, et al. Among authors: gu bj. J Immunol Methods. 2007 Aug 31;325(1-2):67-77. doi: 10.1016/j.jim.2007.06.002. Epub 2007 Jun 26. J Immunol Methods. 2007. PMID: 17618646
Genetics of the P2X7 receptor and human disease.
Fuller SJ, Stokes L, Skarratt KK, Gu BJ, Wiley JS. Fuller SJ, et al. Among authors: gu bj. Purinergic Signal. 2009 Jun;5(2):257-62. doi: 10.1007/s11302-009-9136-4. Epub 2009 Mar 25. Purinergic Signal. 2009. PMID: 19319666 Free PMC article.
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