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4,242 results
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Structure-activity based study of the Smac-binding pocket within the BIR3 domain of XIAP.
Wist AD, Gu L, Riedl SJ, Shi Y, McLendon GL. Wist AD, et al. Among authors: gu l. Bioorg Med Chem. 2007 Apr 15;15(8):2935-43. doi: 10.1016/j.bmc.2007.02.010. Epub 2007 Feb 11. Bioorg Med Chem. 2007. PMID: 17336535
Structural basis of competitive recognition of p53 and MDM2 by HAUSP/USP7: implications for the regulation of the p53-MDM2 pathway.
Hu M, Gu L, Li M, Jeffrey PD, Gu W, Shi Y. Hu M, et al. Among authors: gu l, gu w. PLoS Biol. 2006 Feb;4(2):e27. doi: 10.1371/journal.pbio.0040027. Epub 2006 Jan 17. PLoS Biol. 2006. PMID: 16402859 Free PMC article.
Crystal structure of a FYVE-type zinc finger domain from the caspase regulator CARP2.
Tibbetts MD, Shiozaki EN, Gu L, McDonald ER 3rd, El-Deiry WS, Shi Y. Tibbetts MD, et al. Among authors: gu l. Structure. 2004 Dec;12(12):2257-63. doi: 10.1016/j.str.2004.10.007. Structure. 2004. PMID: 15576038
Structure of the BRCT repeats of BRCA1 bound to a BACH1 phosphopeptide: implications for signaling.
Shiozaki EN, Gu L, Yan N, Shi Y. Shiozaki EN, et al. Among authors: gu l. Mol Cell. 2004 May 7;14(3):405-12. doi: 10.1016/s1097-2765(04)00238-2. Mol Cell. 2004. PMID: 15125843
Structural, biochemical, and functional analyses of CED-9 recognition by the proapoptotic proteins EGL-1 and CED-4.
Yan N, Gu L, Kokel D, Chai J, Li W, Han A, Chen L, Xue D, Shi Y. Yan N, et al. Among authors: gu l. Mol Cell. 2004 Sep 24;15(6):999-1006. doi: 10.1016/j.molcel.2004.08.022. Mol Cell. 2004. PMID: 15383288
Engineered Thermoplasma acidophilum factor F3 mimics human aminopeptidase N (APN) as a target for anticancer drug development.
Su J, Wang Q, Feng J, Zhang C, Zhu D, Wei T, Xu W, Gu L. Su J, et al. Among authors: gu l. Bioorg Med Chem. 2011 May 1;19(9):2991-6. doi: 10.1016/j.bmc.2011.03.028. Epub 2011 Mar 21. Bioorg Med Chem. 2011. PMID: 21493078
Molecular mechanism of AHSP-mediated stabilization of alpha-hemoglobin.
Feng L, Gell DA, Zhou S, Gu L, Kong Y, Li J, Hu M, Yan N, Lee C, Rich AM, Armstrong RS, Lay PA, Gow AJ, Weiss MJ, Mackay JP, Shi Y. Feng L, et al. Among authors: gu l. Cell. 2004 Nov 24;119(5):629-40. doi: 10.1016/j.cell.2004.11.025. Cell. 2004. PMID: 15550245
Structural analysis of a rhomboid family intramembrane protease reveals a gating mechanism for substrate entry.
Wu Z, Yan N, Feng L, Oberstein A, Yan H, Baker RP, Gu L, Jeffrey PD, Urban S, Shi Y. Wu Z, et al. Among authors: gu l. Nat Struct Mol Biol. 2006 Dec;13(12):1084-91. doi: 10.1038/nsmb1179. Epub 2006 Nov 10. Nat Struct Mol Biol. 2006. PMID: 17099694
Structure of oxidized alpha-haemoglobin bound to AHSP reveals a protective mechanism for haem.
Feng L, Zhou S, Gu L, Gell DA, Mackay JP, Weiss MJ, Gow AJ, Shi Y. Feng L, et al. Among authors: gu l. Nature. 2005 Jun 2;435(7042):697-701. doi: 10.1038/nature03609. Nature. 2005. PMID: 15931225
Structure of the CED-4-CED-9 complex provides insights into programmed cell death in Caenorhabditis elegans.
Yan N, Chai J, Lee ES, Gu L, Liu Q, He J, Wu JW, Kokel D, Li H, Hao Q, Xue D, Shi Y. Yan N, et al. Among authors: gu l. Nature. 2005 Oct 6;437(7060):831-7. doi: 10.1038/nature04002. Nature. 2005. PMID: 16208361
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