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Acetylation inactivates the transcriptional repressor BCL6.
Bereshchenko OR, Gu W, Dalla-Favera R. Bereshchenko OR, et al. Nat Genet. 2002 Dec;32(4):606-13. doi: 10.1038/ng1018. Epub 2002 Oct 28. Nat Genet. 2002. PMID: 12402037
Binding and suppression of the Myc transcriptional activation domain by p107.
Gu W, Bhatia K, Magrath IT, Dang CV, Dalla-Favera R. Gu W, et al. Science. 1994 Apr 8;264(5156):251-4. doi: 10.1126/science.8146655. Science. 1994. PMID: 8146655
Opposite regulation of gene transcription and cell proliferation by c-Myc and Max.
Gu W, Cechova K, Tassi V, Dalla-Favera R. Gu W, et al. Proc Natl Acad Sci U S A. 1993 Apr 1;90(7):2935-9. doi: 10.1073/pnas.90.7.2935. Proc Natl Acad Sci U S A. 1993. PMID: 8385351 Free PMC article.
Synergistic activation of transcription by CBP and p53.
Gu W, Shi XL, Roeder RG. Gu W, et al. Nature. 1997 Jun 19;387(6635):819-23. doi: 10.1038/42972. Nature. 1997. PMID: 9194564
The function of PML in p53-dependent apoptosis.
Guo A, Salomoni P, Luo J, Shih A, Zhong S, Gu W, Pandolfi PP. Guo A, et al. Nat Cell Biol. 2000 Oct;2(10):730-6. doi: 10.1038/35036365. Nat Cell Biol. 2000. PMID: 11025664
Deacetylation of p53 modulates its effect on cell growth and apoptosis.
Luo J, Su F, Chen D, Shiloh A, Gu W. Luo J, et al. Nature. 2000 Nov 16;408(6810):377-81. doi: 10.1038/35042612. Nature. 2000. PMID: 11099047
Negative control of p53 by Sir2alpha promotes cell survival under stress.
Luo J, Nikolaev AY, Imai S, Chen D, Su F, Shiloh A, Guarente L, Gu W. Luo J, et al. Cell. 2001 Oct 19;107(2):137-48. doi: 10.1016/s0092-8674(01)00524-4. Cell. 2001. PMID: 11672522
Deubiquitination of p53 by HAUSP is an important pathway for p53 stabilization.
Li M, Chen D, Shiloh A, Luo J, Nikolaev AY, Qin J, Gu W. Li M, et al. Nature. 2002 Apr 11;416(6881):648-53. doi: 10.1038/nature737. Epub 2002 Mar 31. Nature. 2002. PMID: 11923872
Acetylation of p53 inhibits its ubiquitination by Mdm2.
Li M, Luo J, Brooks CL, Gu W. Li M, et al. J Biol Chem. 2002 Dec 27;277(52):50607-11. doi: 10.1074/jbc.C200578200. Epub 2002 Nov 5. J Biol Chem. 2002. PMID: 12421820
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