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Inhibition of translation initiation complex formation by GE81112 unravels a 16S rRNA structural switch involved in P-site decoding.
Fabbretti A, Schedlbauer A, Brandi L, Kaminishi T, Giuliodori AM, Garofalo R, Ochoa-Lizarralde B, Takemoto C, Yokoyama S, Connell SR, Gualerzi CO, Fucini P. Fabbretti A, et al. Among authors: gualerzi co. Proc Natl Acad Sci U S A. 2016 Apr 19;113(16):E2286-95. doi: 10.1073/pnas.1521156113. Epub 2016 Apr 6. Proc Natl Acad Sci U S A. 2016. PMID: 27071098 Free PMC article.
Involvement of protein IF2 N domain in ribosomal subunit joining revealed from architecture and function of the full-length initiation factor.
Simonetti A, Marzi S, Billas IM, Tsai A, Fabbretti A, Myasnikov AG, Roblin P, Vaiana AC, Hazemann I, Eiler D, Steitz TA, Puglisi JD, Gualerzi CO, Klaholz BP. Simonetti A, et al. Among authors: gualerzi co. Proc Natl Acad Sci U S A. 2013 Sep 24;110(39):15656-61. doi: 10.1073/pnas.1309578110. Epub 2013 Sep 12. Proc Natl Acad Sci U S A. 2013. PMID: 24029017 Free PMC article.
Translation initiation without IF2-dependent GTP hydrolysis.
Fabbretti A, Brandi L, Milón P, Spurio R, Pon CL, Gualerzi CO. Fabbretti A, et al. Among authors: gualerzi co. Nucleic Acids Res. 2012 Sep;40(16):7946-55. doi: 10.1093/nar/gks569. Epub 2012 Jun 20. Nucleic Acids Res. 2012. PMID: 22723375 Free PMC article.
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