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Inhibition of podocyte FAK protects against proteinuria and foot process effacement.
Ma H, Togawa A, Soda K, Zhang J, Lee S, Ma M, Yu Z, Ardito T, Czyzyk J, Diggs L, Joly D, Hatakeyama S, Kawahara E, Holzman L, Guan JL, Ishibe S. Ma H, et al. Among authors: guan jl. J Am Soc Nephrol. 2010 Jul;21(7):1145-56. doi: 10.1681/ASN.2009090991. Epub 2010 Jun 3. J Am Soc Nephrol. 2010. PMID: 20522532 Free PMC article.
Downregulation of FIP200 induces apoptosis of glioblastoma cells and microvascular endothelial cells by enhancing Pyk2 activity.
Wang D, Olman MA, Stewart J Jr, Tipps R, Huang P, Sanders PW, Toline E, Prayson RA, Lee J, Weil RJ, Palmer CA, Gillespie GY, Liu WM, Pieper RO, Guan JL, Gladson CL. Wang D, et al. Among authors: guan jl. PLoS One. 2011;6(5):e19629. doi: 10.1371/journal.pone.0019629. Epub 2011 May 13. PLoS One. 2011. PMID: 21602932 Free PMC article.
VEGF-induced vascular permeability is mediated by FAK.
Chen XL, Nam JO, Jean C, Lawson C, Walsh CT, Goka E, Lim ST, Tomar A, Tancioni I, Uryu S, Guan JL, Acevedo LM, Weis SM, Cheresh DA, Schlaepfer DD. Chen XL, et al. Among authors: guan jl. Dev Cell. 2012 Jan 17;22(1):146-57. doi: 10.1016/j.devcel.2011.11.002. Dev Cell. 2012. PMID: 22264731 Free PMC article.
Signal transduction by focal adhesion kinase in cancer.
Zhao J, Guan JL. Zhao J, et al. Among authors: guan jl. Cancer Metastasis Rev. 2009 Jun;28(1-2):35-49. doi: 10.1007/s10555-008-9165-4. Cancer Metastasis Rev. 2009. PMID: 19169797 Review.
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