Guan S - Search Results

1

Novel ALK inhibitor AZD3463 inhibits neuroblastoma growth by overcoming crizotinib resistance and inducing apoptosis.

Wang Y, Wang L, Guan S, Cao W, Wang H, Chen Z, Zhao Y, Yu Y, Zhang H, Pang JC, Huang SL, Akiyama Y, Yang Y, Sun W, Xu X, Shi Y, Zhang H, Kim ES, Muscal JA, Lu F, Yang J. Wang Y, et al. Among authors: guan s. Sci Rep. 2016 Jan 20;6:19423. doi: 10.1038/srep19423. Sci Rep. 2016. PMID: 26786851 Free PMC article.

2

mTOR ATP-competitive inhibitor INK128 inhibits neuroblastoma growth via blocking mTORC signaling.

Zhang H, Dou J, Yu Y, Zhao Y, Fan Y, Cheng J, Xu X, Liu W, Guan S, Chen Z, shi Y, Patel R, Vasudevan SA, Zage PE, Zhang H, Nuchtern JG, Kim ES, Fu S, Yang J. Zhang H, et al. Among authors: guan s. Apoptosis. 2015 Jan;20(1):50-62. doi: 10.1007/s10495-014-1066-0. Apoptosis. 2015. PMID: 25425103 Free PMC article.

3

Novel proteasome inhibitor ixazomib sensitizes neuroblastoma cells to doxorubicin treatment.

Li H, Chen Z, Hu T, Wang L, Yu Y, Zhao Y, Sun W, Guan S, Pang JC, Woodfield SE, Liu Q, Yang J. Li H, et al. Among authors: guan s. Sci Rep. 2016 Sep 30;6:34397. doi: 10.1038/srep34397. Sci Rep. 2016. PMID: 27687684 Free PMC article.

4

Second-generation proteasome inhibitor carfilzomib sensitizes neuroblastoma cells to doxorubicin-induced apoptosis.

Guan S, Zhao Y, Lu J, Yu Y, Sun W, Mao X, Chen Z, Xu X, Pan J, Sun S, Yang J. Guan S, et al. Oncotarget. 2016 Nov 15;7(46):75914-75925. doi: 10.18632/oncotarget.12427. Oncotarget. 2016. PMID: 27713150 Free PMC article.

5

Novel MDM2 inhibitor SAR405838 (MI-773) induces p53-mediated apoptosis in neuroblastoma.

Lu J, Guan S, Zhao Y, Yu Y, Wang Y, Shi Y, Mao X, Yang KL, Sun W, Xu X, Yi JS, Yang T, Yang J, Nuchtern JG. Lu J, et al. Among authors: guan s. Oncotarget. 2016 Dec 13;7(50):82757-82769. doi: 10.18632/oncotarget.12634. Oncotarget. 2016. PMID: 27764791 Free PMC article.

6

Novel multi-targeted ErbB family inhibitor afatinib blocks EGF-induced signaling and induces apoptosis in neuroblastoma.

Mao X, Chen Z, Zhao Y, Yu Y, Guan S, Woodfield SE, Vasudevan SA, Tao L, Pang JC, Lu J, Zhang H, Zhang F, Yang J. Mao X, et al. Among authors: guan s. Oncotarget. 2017 Jan 3;8(1):1555-1568. doi: 10.18632/oncotarget.13657. Oncotarget. 2017. PMID: 27902463 Free PMC article.

7

Novel Src/Abl tyrosine kinase inhibitor bosutinib suppresses neuroblastoma growth via inhibiting Src/Abl signaling.

Bieerkehazhi S, Chen Z, Zhao Y, Yu Y, Zhang H, Vasudevan SA, Woodfield SE, Tao L, Yi JS, Muscal JA, Pang JC, Guan S, Zhang H, Nuchtern JG, Li H, Li H, Yang J. Bieerkehazhi S, et al. Among authors: guan s. Oncotarget. 2017 Jan 3;8(1):1469-1480. doi: 10.18632/oncotarget.13643. Oncotarget. 2017. PMID: 27903968 Free PMC article.

8

Wip1 inhibitor GSK2830371 inhibits neuroblastoma growth by inducing Chk2/p53-mediated apoptosis.

Chen Z, Wang L, Yao D, Yang T, Cao WM, Dou J, Pang JC, Guan S, Zhang H, Yu Y, Zhao Y, Wang Y, Xu X, Shi Y, Patel R, Zhang H, Vasudevan SA, Liu S, Yang J, Nuchtern JG. Chen Z, et al. Among authors: guan s. Sci Rep. 2016 Dec 19;6:38011. doi: 10.1038/srep38011. Sci Rep. 2016. PMID: 27991505 Free PMC article.

9

The second-generation ALK inhibitor alectinib effectively induces apoptosis in human neuroblastoma cells and inhibits tumor growth in a TH-MYCN transgenic neuroblastoma mouse model.

Lu J, Guan S, Zhao Y, Yu Y, Woodfield SE, Zhang H, Yang KL, Bieerkehazhi S, Qi L, Li X, Gu J, Xu X, Jin J, Muscal JA, Yang T, Xu GT, Yang J. Lu J, et al. Among authors: guan s. Cancer Lett. 2017 Aug 1;400:61-68. doi: 10.1016/j.canlet.2017.04.022. Epub 2017 Apr 26. Cancer Lett. 2017. PMID: 28455243 Free PMC article.

10

TAK1 inhibitor 5Z-7-oxozeaenol sensitizes cervical cancer to doxorubicin-induced apoptosis.

Guan S, Lu J, Zhao Y, Woodfield SE, Zhang H, Xu X, Yu Y, Zhao J, Bieerkehazhi S, Liang H, Yang J, Zhang F, Sun S. Guan S, et al. Oncotarget. 2017 May 16;8(20):33666-33675. doi: 10.18632/oncotarget.16895. Oncotarget. 2017. PMID: 28430599 Free PMC article.

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