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Control of the SCF(Skp2-Cks1) ubiquitin ligase by the APC/C(Cdh1) ubiquitin ligase.
Bashir T, Dorrello NV, Amador V, Guardavaccaro D, Pagano M. Bashir T, et al. Nature. 2004 Mar 11;428(6979):190-3. doi: 10.1038/nature02330. Nature. 2004. PMID: 15014502
Identification of a family of human F-box proteins.
Cenciarelli C, Chiaur DS, Guardavaccaro D, Parks W, Vidal M, Pagano M. Cenciarelli C, et al. Curr Biol. 1999 Oct 21;9(20):1177-9. doi: 10.1016/S0960-9822(00)80020-2. Curr Biol. 1999. PMID: 10531035
Control of meiotic and mitotic progression by the F box protein beta-Trcp1 in vivo.
Guardavaccaro D, Kudo Y, Boulaire J, Barchi M, Busino L, Donzelli M, Margottin-Goguet F, Jackson PK, Yamasaki L, Pagano M. Guardavaccaro D, et al. Dev Cell. 2003 Jun;4(6):799-812. doi: 10.1016/s1534-5807(03)00154-0. Dev Cell. 2003. PMID: 12791266
Degradation of Cdc25A by beta-TrCP during S phase and in response to DNA damage.
Busino L, Donzelli M, Chiesa M, Guardavaccaro D, Ganoth D, Dorrello NV, Hershko A, Pagano M, Draetta GF. Busino L, et al. Nature. 2003 Nov 6;426(6962):87-91. doi: 10.1038/nature02082. Nature. 2003. PMID: 14603323
Oncogenic aberrations of cullin-dependent ubiquitin ligases.
Guardavaccaro D, Pagano M. Guardavaccaro D, et al. Oncogene. 2004 Mar 15;23(11):2037-49. doi: 10.1038/sj.onc.1207413. Oncogene. 2004. PMID: 15021891 Review.
Stabilizers and destabilizers controlling cell cycle oscillators.
Guardavaccaro D, Pagano M. Guardavaccaro D, et al. Mol Cell. 2006 Apr 7;22(1):1-4. doi: 10.1016/j.molcel.2006.03.017. Mol Cell. 2006. PMID: 16600864 Review.
Degradation of Id2 by the anaphase-promoting complex couples cell cycle exit and axonal growth.
Lasorella A, Stegmüller J, Guardavaccaro D, Liu G, Carro MS, Rothschild G, de la Torre-Ubieta L, Pagano M, Bonni A, Iavarone A. Lasorella A, et al. Nature. 2006 Jul 27;442(7101):471-4. doi: 10.1038/nature04895. Epub 2006 Jun 28. Nature. 2006. PMID: 16810178
APC/C(Cdh1) targets Id2 for degradation through a destruction box motif (D box) that is conserved in Id1 and Id4. Depletion of Cdh1 stabilizes Id proteins in neurons, whereas Id2 D-box mutants are impaired for Cdh1 binding and remain stable in cells that exit from t …
APC/C(Cdh1) targets Id2 for degradation through a destruction box motif (D box) that is conserved in Id1 and Id4. Depletion of Cdh1 s …
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