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A therapeutic role for sirtuins in diseases of aging?
Westphal CH, Dipp MA, Guarente L. Westphal CH, et al. Trends Biochem Sci. 2007 Dec;32(12):555-60. doi: 10.1016/j.tibs.2007.09.008. Epub 2007 Nov 5. Trends Biochem Sci. 2007. PMID: 17980602 Review.
Genetic pathways that regulate ageing in model organisms.
Guarente L, Kenyon C. Guarente L, et al. Nature. 2000 Nov 9;408(6809):255-62. doi: 10.1038/35041700. Nature. 2000. PMID: 11089983 Review.
Multiple domains mediate heme control of the yeast activator HAP1.
Haldi ML, Guarente L. Haldi ML, et al. Mol Gen Genet. 1995 Jul 28;248(2):229-35. doi: 10.1007/BF02190805. Mol Gen Genet. 1995. PMID: 7651346
Accelerated aging and nucleolar fragmentation in yeast sgs1 mutants.
Sinclair DA, Mills K, Guarente L. Sinclair DA, et al. Science. 1997 Aug 29;277(5330):1313-6. doi: 10.1126/science.277.5330.1313. Science. 1997. PMID: 9271578
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