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Calorie restriction, SIRT1 and metabolism: understanding longevity.
Bordone L, Guarente L. Bordone L, et al. Nat Rev Mol Cell Biol. 2005 Apr;6(4):298-305. doi: 10.1038/nrm1616. Nat Rev Mol Cell Biol. 2005. PMID: 15768047 Review.
Sirtuins and beta-cell function.
Bordone L, Guarente L. Bordone L, et al. Diabetes Obes Metab. 2007 Nov;9 Suppl 2:23-7. doi: 10.1111/j.1463-1326.2007.00769.x. Diabetes Obes Metab. 2007. PMID: 17919175
A therapeutic role for sirtuins in diseases of aging?
Westphal CH, Dipp MA, Guarente L. Westphal CH, et al. Trends Biochem Sci. 2007 Dec;32(12):555-60. doi: 10.1016/j.tibs.2007.09.008. Epub 2007 Nov 5. Trends Biochem Sci. 2007. PMID: 17980602 Review.
The place of genetics in ageing research.
Barzilai N, Guarente L, Kirkwood TB, Partridge L, Rando TA, Slagboom PE. Barzilai N, et al. Nat Rev Genet. 2012 Jul 10;13(8):589-94. doi: 10.1038/nrg3290. Nat Rev Genet. 2012. PMID: 22777128 Review.
Genetic pathways that regulate ageing in model organisms.
Guarente L, Kenyon C. Guarente L, et al. Nature. 2000 Nov 9;408(6809):255-62. doi: 10.1038/35041700. Nature. 2000. PMID: 11089983 Review.
Mutations in the WRN gene in mice accelerate mortality in a p53-null background.
Lombard DB, Beard C, Johnson B, Marciniak RA, Dausman J, Bronson R, Buhlmann JE, Lipman R, Curry R, Sharpe A, Jaenisch R, Guarente L. Lombard DB, et al. Mol Cell Biol. 2000 May;20(9):3286-91. doi: 10.1128/mcb.20.9.3286-3291.2000. Mol Cell Biol. 2000. PMID: 10757812 Free PMC article.
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