Guarente L - Search Results

1

Proteolipid protein is required for transport of sirtuin 2 into CNS myelin.

Werner HB, Kuhlmann K, Shen S, Uecker M, Schardt A, Dimova K, Orfaniotou F, Dhaunchak A, Brinkmann BG, Möbius W, Guarente L, Casaccia-Bonnefil P, Jahn O, Nave KA. Werner HB, et al. Among authors: guarente l. J Neurosci. 2007 Jul 18;27(29):7717-30. doi: 10.1523/JNEUROSCI.1254-07.2007. J Neurosci. 2007. PMID: 17634366 Free PMC article.

2

SIRT1 protects against α-synuclein aggregation by activating molecular chaperones.

Donmez G, Arun A, Chung CY, McLean PJ, Lindquist S, Guarente L. Donmez G, et al. Among authors: guarente l. J Neurosci. 2012 Jan 4;32(1):124-32. doi: 10.1523/JNEUROSCI.3442-11.2012. J Neurosci. 2012. PMID: 22219275 Free PMC article. Retracted.

3

SIRT1 suppresses beta-amyloid production by activating the alpha-secretase gene ADAM10.

Donmez G, Wang D, Cohen DE, Guarente L. Donmez G, et al. Among authors: guarente l. Cell. 2010 Jul 23;142(2):320-32. doi: 10.1016/j.cell.2010.06.020. Cell. 2010. PMID: 20655472 Free PMC article. Retracted.

4

Neuronal SIRT1 regulates endocrine and behavioral responses to calorie restriction.

Cohen DE, Supinski AM, Bonkowski MS, Donmez G, Guarente LP. Cohen DE, et al. Genes Dev. 2009 Dec 15;23(24):2812-7. doi: 10.1101/gad.1839209. Genes Dev. 2009. PMID: 20008932 Free PMC article.

5

The role of calorie restriction and SIRT1 in prion-mediated neurodegeneration.

Chen D, Steele AD, Hutter G, Bruno J, Govindarajan A, Easlon E, Lin SJ, Aguzzi A, Lindquist S, Guarente L. Chen D, et al. Among authors: guarente l. Exp Gerontol. 2008 Dec;43(12):1086-93. doi: 10.1016/j.exger.2008.08.050. Epub 2008 Aug 30. Exp Gerontol. 2008. PMID: 18799131 Free PMC article.

6

Aging and disease: connections to sirtuins.

Donmez G, Guarente L. Donmez G, et al. Among authors: guarente l. Aging Cell. 2010 Apr;9(2):285-90. doi: 10.1111/j.1474-9726.2010.00548.x. Aging Cell. 2010. PMID: 20409078 Free article. Review.

7

Increase in activity during calorie restriction requires Sirt1.

Chen D, Steele AD, Lindquist S, Guarente L. Chen D, et al. Among authors: guarente l. Science. 2005 Dec 9;310(5754):1641. doi: 10.1126/science.1118357. Science. 2005. PMID: 16339438

8

Hepatic overexpression of SIRT1 in mice attenuates endoplasmic reticulum stress and insulin resistance in the liver.

Li Y, Xu S, Giles A, Nakamura K, Lee JW, Hou X, Donmez G, Li J, Luo Z, Walsh K, Guarente L, Zang M. Li Y, et al. Among authors: guarente l. FASEB J. 2011 May;25(5):1664-79. doi: 10.1096/fj.10-173492. Epub 2011 Feb 14. FASEB J. 2011. PMID: 21321189 Free PMC article.

9

SIRT2 ablation has no effect on tubulin acetylation in brain, cholesterol biosynthesis or the progression of Huntington's disease phenotypes in vivo.

Bobrowska A, Donmez G, Weiss A, Guarente L, Bates G. Bobrowska A, et al. Among authors: guarente l. PLoS One. 2012;7(4):e34805. doi: 10.1371/journal.pone.0034805. Epub 2012 Apr 12. PLoS One. 2012. PMID: 22511966 Free PMC article.

10

SIRT1 in neurodevelopment and brain senescence.

Herskovits AZ, Guarente L. Herskovits AZ, et al. Among authors: guarente l. Neuron. 2014 Feb 5;81(3):471-83. doi: 10.1016/j.neuron.2014.01.028. Neuron. 2014. PMID: 24507186 Free PMC article. Review.

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