Gudkov AV - Search Results

1

Unsupervised learning of aging principles from longitudinal data.

Avchaciov K, Antoch MP, Andrianova EL, Tarkhov AE, Menshikov LI, Burmistrova O, Gudkov AV, Fedichev PO. Avchaciov K, et al. Among authors: gudkov av. Nat Commun. 2022 Nov 1;13(1):6529. doi: 10.1038/s41467-022-34051-9. Nat Commun. 2022. PMID: 36319638 Free PMC article.

2

BMAL1-dependent circadian oscillation of nuclear CLOCK: posttranslational events induced by dimerization of transcriptional activators of the mammalian clock system.

Kondratov RV, Chernov MV, Kondratova AA, Gorbacheva VY, Gudkov AV, Antoch MP. Kondratov RV, et al. Among authors: gudkov av. Genes Dev. 2003 Aug 1;17(15):1921-32. doi: 10.1101/gad.1099503. Genes Dev. 2003. PMID: 12897057 Free PMC article.

3

Circadian sensitivity to the chemotherapeutic agent cyclophosphamide depends on the functional status of the CLOCK/BMAL1 transactivation complex.

Gorbacheva VY, Kondratov RV, Zhang R, Cherukuri S, Gudkov AV, Takahashi JS, Antoch MP. Gorbacheva VY, et al. Among authors: gudkov av. Proc Natl Acad Sci U S A. 2005 Mar 1;102(9):3407-12. doi: 10.1073/pnas.0409897102. Epub 2005 Feb 2. Proc Natl Acad Sci U S A. 2005. PMID: 15689397 Free PMC article.

4

A small molecule inhibitor of p53 stimulates amplification of hematopoietic stem cells but does not promote tumor development in mice.

Leonova KI, Shneyder J, Antoch MP, Toshkov IA, Novototskaya LR, Komarov PG, Komarova EA, Gudkov AV. Leonova KI, et al. Among authors: gudkov av. Cell Cycle. 2010 Apr 1;9(7):1434-43. doi: 10.4161/cc.9.7.11508. Epub 2010 Apr 1. Cell Cycle. 2010. PMID: 20404530 Free PMC article.

5

Selenium is a modulator of circadian clock that protects mice from the toxicity of a chemotherapeutic drug via upregulation of the core clock protein, BMAL1.

Hu Y, Spengler ML, Kuropatwinski KK, Comas-Soberats M, Jackson M, Chernov MV, Gleiberman AS, Fedtsova N, Rustum YM, Gudkov AV, Antoch MP. Hu Y, et al. Among authors: gudkov av. Oncotarget. 2011 Dec;2(12):1279-90. doi: 10.18632/oncotarget.411. Oncotarget. 2011. PMID: 22249125 Free PMC article.

6

Core circadian protein CLOCK is a positive regulator of NF-κB-mediated transcription.

Spengler ML, Kuropatwinski KK, Comas M, Gasparian AV, Fedtsova N, Gleiberman AS, Gitlin II, Artemicheva NM, Deluca KA, Gudkov AV, Antoch MP. Spengler ML, et al. Among authors: gudkov av. Proc Natl Acad Sci U S A. 2012 Sep 11;109(37):E2457-65. doi: 10.1073/pnas.1206274109. Epub 2012 Aug 15. Proc Natl Acad Sci U S A. 2012. PMID: 22895791 Free PMC article.

7

New nanoformulation of rapamycin Rapatar extends lifespan in homozygous p53-/- mice by delaying carcinogenesis.

Comas M, Toshkov I, Kuropatwinski KK, Chernova OB, Polinsky A, Blagosklonny MV, Gudkov AV, Antoch MP. Comas M, et al. Among authors: gudkov av. Aging (Albany NY). 2012 Oct;4(10):715-22. doi: 10.18632/aging.100496. Aging (Albany NY). 2012. PMID: 23117593 Free PMC article.

8

Rapamycin extends lifespan and delays tumorigenesis in heterozygous p53+/- mice.

Komarova EA, Antoch MP, Novototskaya LR, Chernova OB, Paszkiewicz G, Leontieva OV, Blagosklonny MV, Gudkov AV. Komarova EA, et al. Among authors: gudkov av. Aging (Albany NY). 2012 Oct;4(10):709-14. doi: 10.18632/aging.100498. Aging (Albany NY). 2012. PMID: 23123616 Free PMC article.

9

Senescent cells expose and secrete an oxidized form of membrane-bound vimentin as revealed by a natural polyreactive antibody.

Frescas D, Roux CM, Aygun-Sunar S, Gleiberman AS, Krasnov P, Kurnasov OV, Strom E, Virtuoso LP, Wrobel M, Osterman AL, Antoch MP, Mett V, Chernova OB, Gudkov AV. Frescas D, et al. Among authors: gudkov av. Proc Natl Acad Sci U S A. 2017 Feb 28;114(9):E1668-E1677. doi: 10.1073/pnas.1614661114. Epub 2017 Feb 13. Proc Natl Acad Sci U S A. 2017. PMID: 28193858 Free PMC article.

10

Physiological frailty index (PFI): quantitative in-life estimate of individual biological age in mice.

Antoch MP, Wrobel M, Kuropatwinski KK, Gitlin I, Leonova KI, Toshkov I, Gleiberman AS, Hutson AD, Chernova OB, Gudkov AV. Antoch MP, et al. Among authors: gudkov av. Aging (Albany NY). 2017 Mar 19;9(3):615-626. doi: 10.18632/aging.101206. Aging (Albany NY). 2017. PMID: 28325885 Free PMC article.

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