Guengerich FP - Search Results

1

Applying mechanisms of chemical toxicity to predict drug safety.

Guengerich FP, MacDonald JS. Guengerich FP, et al. Chem Res Toxicol. 2007 Mar;20(3):344-69. doi: 10.1021/tx600260a. Epub 2007 Feb 16. Chem Res Toxicol. 2007. PMID: 17302443 Review.

2

Glutathione conjugation of aflatoxin B1 exo- and endo-epoxides by rat and human glutathione S-transferases.

Raney KD, Meyer DJ, Ketterer B, Harris TM, Guengerich FP. Raney KD, et al. Among authors: guengerich fp. Chem Res Toxicol. 1992 Jul-Aug;5(4):470-8. doi: 10.1021/tx00028a004. Chem Res Toxicol. 1992. PMID: 1391613

3

The endo-8,9-epoxide of aflatoxin B1: a new metabolite.

Raney KD, Coles B, Guengerich FP, Harris TM. Raney KD, et al. Among authors: guengerich fp. Chem Res Toxicol. 1992 May-Jun;5(3):333-5. doi: 10.1021/tx00027a002. Chem Res Toxicol. 1992. PMID: 1504254 No abstract available.

4

Roles of the vinyl chloride oxidation products 1-chlorooxirane and 2-chloroacetaldehyde in the in vitro formation of etheno adducts of nucleic acid bases [corrected].

Guengerich FP. Guengerich FP. Chem Res Toxicol. 1992 Jan-Feb;5(1):2-5. doi: 10.1021/tx00025a001. Chem Res Toxicol. 1992. PMID: 1581532 No abstract available.

5

Oxidation of aflatoxins and sterigmatocystin by human liver microsomes: significance of aflatoxin Q1 as a detoxication product of aflatoxin B1.

Raney KD, Shimada T, Kim DH, Groopman JD, Harris TM, Guengerich FP. Raney KD, et al. Among authors: guengerich fp. Chem Res Toxicol. 1992 Mar-Apr;5(2):202-10. doi: 10.1021/tx00026a009. Chem Res Toxicol. 1992. PMID: 1643250

6

Structure of formamidopyrimidine adducts as determined by NMR using specifically 15N-labeled guanosine.

Humphreys WG, Guengerich FP. Humphreys WG, et al. Among authors: guengerich fp. Chem Res Toxicol. 1991 Nov-Dec;4(6):632-6. doi: 10.1021/tx00024a005. Chem Res Toxicol. 1991. PMID: 1807445 No abstract available.

7

Oxidation of toxic and carcinogenic chemicals by human cytochrome P-450 enzymes.

Guengerich FP, Shimada T. Guengerich FP, et al. Chem Res Toxicol. 1991 Jul-Aug;4(4):391-407. doi: 10.1021/tx00022a001. Chem Res Toxicol. 1991. PMID: 1912325 Review. No abstract available.

8

Mechanism-based inactivation of human liver microsomal cytochrome P-450 IIIA4 by gestodene.

Guengerich FP. Guengerich FP. Chem Res Toxicol. 1990 Jul-Aug;3(4):363-71. doi: 10.1021/tx00016a015. Chem Res Toxicol. 1990. PMID: 2133086

9

Comparison of rates of enzymatic oxidation of aflatoxin B1, aflatoxin G1, and sterigmatocystin and activities of the epoxides in forming guanyl-N7 adducts and inducing different genetic responses.

Baertschi SW, Raney KD, Shimada T, Harris TM, Guengerich FP. Baertschi SW, et al. Among authors: guengerich fp. Chem Res Toxicol. 1989 Mar-Apr;2(2):114-2. doi: 10.1021/tx00008a008. Chem Res Toxicol. 1989. PMID: 2519710

10

Enhancement of bacterial mutagenicity of bifunctional alkylating agents by expression of mammalian glutathione S-transferase.

Thier R, Müller M, Taylor JB, Pemble SE, Ketterer B, Guengerich FP. Thier R, et al. Among authors: guengerich fp. Chem Res Toxicol. 1995 Apr-May;8(3):465-72. doi: 10.1021/tx00045a019. Chem Res Toxicol. 1995. PMID: 7578934

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