Guengerich FP - Search Results

1

Contributions of human enzymes in carcinogen metabolism.

Rendic S, Guengerich FP. Rendic S, et al. Among authors: guengerich fp. Chem Res Toxicol. 2012 Jul 16;25(7):1316-83. doi: 10.1021/tx300132k. Epub 2012 May 10. Chem Res Toxicol. 2012. PMID: 22531028 Free PMC article. Review.

2

Oxidation of toxic and carcinogenic chemicals by human cytochrome P-450 enzymes.

Guengerich FP, Shimada T. Guengerich FP, et al. Chem Res Toxicol. 1991 Jul-Aug;4(4):391-407. doi: 10.1021/tx00022a001. Chem Res Toxicol. 1991. PMID: 1912325 Review. No abstract available.

3

Oxidation of benzo[a]pyrene by recombinant human cytochrome P450 enzymes.

Bauer E, Guo Z, Ueng YF, Bell LC, Zeldin D, Guengerich FP. Bauer E, et al. Among authors: guengerich fp. Chem Res Toxicol. 1995 Jan-Feb;8(1):136-42. doi: 10.1021/tx00043a018. Chem Res Toxicol. 1995. PMID: 7703357

4

Oxidation of aflatoxin B1 by bacterial recombinant human cytochrome P450 enzymes.

Ueng YF, Shimada T, Yamazaki H, Guengerich FP. Ueng YF, et al. Among authors: guengerich fp. Chem Res Toxicol. 1995 Mar;8(2):218-25. doi: 10.1021/tx00044a006. Chem Res Toxicol. 1995. PMID: 7766804

5

Cytochrome P450 enzymes involved in acetaminophen activation by rat and human liver microsomes and their kinetics.

Patten CJ, Thomas PE, Guy RL, Lee M, Gonzalez FJ, Guengerich FP, Yang CS. Patten CJ, et al. Among authors: guengerich fp. Chem Res Toxicol. 1993 Jul-Aug;6(4):511-8. doi: 10.1021/tx00034a019. Chem Res Toxicol. 1993. PMID: 8374050

6

Roles of human hepatic and pulmonary cytochrome P450 enzymes in the metabolism of the environmental carcinogen 6-nitrochrysene.

Chae YH, Yun CH, Guengerich FP, Kadlubar FF, el-Bayoumy K. Chae YH, et al. Among authors: guengerich fp. Cancer Res. 1993 May 1;53(9):2028-34. Cancer Res. 1993. PMID: 8481905

7

Metabolism of benzo[a]pyrene to trans-7,8-dihydroxy-7, 8-dihydrobenzo[a]pyrene by recombinant human cytochrome P450 1B1 and purified liver epoxide hydrolase.

Shimada T, Gillam EM, Oda Y, Tsumura F, Sutter TR, Guengerich FP, Inoue K. Shimada T, et al. Among authors: guengerich fp. Chem Res Toxicol. 1999 Jul;12(7):623-9. doi: 10.1021/tx990028s. Chem Res Toxicol. 1999. PMID: 10409402

8

Metabolism of ochratoxin A: absence of formation of genotoxic derivatives by human and rat enzymes.

Gautier J, Richoz J, Welti DH, Markovic J, Gremaud E, Guengerich FP, Turesky RJ. Gautier J, et al. Among authors: guengerich fp. Chem Res Toxicol. 2001 Jan;14(1):34-45. doi: 10.1021/tx000070j. Chem Res Toxicol. 2001. PMID: 11170506

9

Metabolism of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline in human hepatocytes: 2-amino-3-methylimidazo[4,5-f]quinoxaline-8-carboxylic acid is a major detoxification pathway catalyzed by cytochrome P450 1A2.

Langouët S, Welti DH, Kerriguy N, Fay LB, Huynh-Ba T, Markovic J, Guengerich FP, Guillouzo A, Turesky RJ. Langouët S, et al. Among authors: guengerich fp. Chem Res Toxicol. 2001 Feb;14(2):211-21. doi: 10.1021/tx000176e. Chem Res Toxicol. 2001. PMID: 11258970

10

Metabolic activation of benzo[c]phenanthrene by cytochrome P450 enzymes in human liver and lung.

Baum M, Amin S, Guengerich FP, Hecht SS, Köhl W, Eisenbrand G. Baum M, et al. Among authors: guengerich fp. Chem Res Toxicol. 2001 Jun;14(6):686-93. doi: 10.1021/tx000240s. Chem Res Toxicol. 2001. PMID: 11409939

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