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A Native Ternary Complex Trapped in a Crystal Reveals the Catalytic Mechanism of a Retaining Glycosyltransferase.
Albesa-Jové D, Mendoza F, Rodrigo-Unzueta A, Gomollón-Bel F, Cifuente JO, Urresti S, Comino N, Gómez H, Romero-García J, Lluch JM, Sancho-Vaello E, Biarnés X, Planas A, Merino P, Masgrau L, Guerin ME. Albesa-Jové D, et al. Among authors: guerin me. Angew Chem Int Ed Engl. 2015 Aug 17;54(34):9898-902. doi: 10.1002/anie.201504617. Epub 2015 Jul 1. Angew Chem Int Ed Engl. 2015. PMID: 26136334
Mechanistic insights into the retaining glucosyl-3-phosphoglycerate synthase from mycobacteria.
Urresti S, Albesa-Jové D, Schaeffer F, Pham HT, Kaur D, Gest P, van der Woerd MJ, Carreras-González A, López-Fernández S, Alzari PM, Brennan PJ, Jackson M, Guerin ME. Urresti S, et al. Among authors: guerin me. J Biol Chem. 2012 Jul 13;287(29):24649-61. doi: 10.1074/jbc.M112.368191. Epub 2012 May 25. J Biol Chem. 2012. PMID: 22637481 Free PMC article.
Structural basis of chitin oligosaccharide deacetylation.
Andrés E, Albesa-Jové D, Biarnés X, Moerschbacher BM, Guerin ME, Planas A. Andrés E, et al. Among authors: guerin me. Angew Chem Int Ed Engl. 2014 Jul 1;53(27):6882-7. doi: 10.1002/anie.201400220. Epub 2014 May 8. Angew Chem Int Ed Engl. 2014. PMID: 24810719
Rv2466c mediates the activation of TP053 to kill replicating and non-replicating Mycobacterium tuberculosis.
Albesa-Jové D, Chiarelli LR, Makarov V, Pasca MR, Urresti S, Mori G, Salina E, Vocat A, Comino N, Mohorko E, Ryabova S, Pfieiffer B, Lopes Ribeiro AL, Rodrigo-Unzueta A, Tersa M, Zanoni G, Buroni S, Altmann KH, Hartkoorn RC, Glockshuber R, Cole ST, Riccardi G, Guerin ME. Albesa-Jové D, et al. Among authors: guerin me. ACS Chem Biol. 2014 Jul 18;9(7):1567-75. doi: 10.1021/cb500149m. Epub 2014 Jun 13. ACS Chem Biol. 2014. PMID: 24877756 Free article.
The Redox State Regulates the Conformation of Rv2466c to Activate the Antitubercular Prodrug TP053.
Albesa-Jové D, Comino N, Tersa M, Mohorko E, Urresti S, Dainese E, Chiarelli LR, Pasca MR, Manganelli R, Makarov V, Riccardi G, Svergun DI, Glockshuber R, Guerin ME. Albesa-Jové D, et al. Among authors: guerin me. J Biol Chem. 2015 Dec 25;290(52):31077-89. doi: 10.1074/jbc.M115.677039. Epub 2015 Nov 6. J Biol Chem. 2015. PMID: 26546681 Free PMC article.
71 results