Guerini D - Search Results

1

Persistent signaling induced by FTY720-phosphate is mediated by internalized S1P1 receptors.

Mullershausen F, Zecri F, Cetin C, Billich A, Guerini D, Seuwen K. Mullershausen F, et al. Among authors: guerini d. Nat Chem Biol. 2009 Jun;5(6):428-34. doi: 10.1038/nchembio.173. Nat Chem Biol. 2009. PMID: 19430484

2

Phosphorylated FTY720 promotes astrocyte migration through sphingosine-1-phosphate receptors.

Mullershausen F, Craveiro LM, Shin Y, Cortes-Cros M, Bassilana F, Osinde M, Wishart WL, Guerini D, Thallmair M, Schwab ME, Sivasankaran R, Seuwen K, Dev KK. Mullershausen F, et al. Among authors: guerini d. J Neurochem. 2007 Aug;102(4):1151-61. doi: 10.1111/j.1471-4159.2007.04629.x. J Neurochem. 2007. PMID: 17488279 Free article.

3

Proton-sensing G-protein-coupled receptors.

Ludwig MG, Vanek M, Guerini D, Gasser JA, Jones CE, Junker U, Hofstetter H, Wolf RM, Seuwen K. Ludwig MG, et al. Among authors: guerini d. Nature. 2003 Sep 4;425(6953):93-8. doi: 10.1038/nature01905. Nature. 2003. PMID: 12955148

4

A potent and selective S1P(1) antagonist with efficacy in experimental autoimmune encephalomyelitis.

Quancard J, Bollbuck B, Janser P, Angst D, Berst F, Buehlmayer P, Streiff M, Beerli C, Brinkmann V, Guerini D, Smith PA, Seabrook TJ, Traebert M, Seuwen K, Hersperger R, Bruns C, Bassilana F, Bigaud M. Quancard J, et al. Among authors: guerini d. Chem Biol. 2012 Sep 21;19(9):1142-51. doi: 10.1016/j.chembiol.2012.07.016. Chem Biol. 2012. PMID: 22999882

5

Second generation S1P pathway modulators: research strategies and clinical developments.

Bigaud M, Guerini D, Billich A, Bassilana F, Brinkmann V. Bigaud M, et al. Among authors: guerini d. Biochim Biophys Acta. 2014 May;1841(5):745-58. doi: 10.1016/j.bbalip.2013.11.001. Epub 2013 Nov 12. Biochim Biophys Acta. 2014. PMID: 24239768 Review.

6

Investigating the molecular mechanisms through which FTY720-P causes persistent S1P1 receptor internalization.

Sykes DA, Riddy DM, Stamp C, Bradley ME, McGuiness N, Sattikar A, Guerini D, Rodrigues I, Glaenzel A, Dowling MR, Mullershausen F, Charlton SJ. Sykes DA, et al. Among authors: guerini d. Br J Pharmacol. 2014 Nov;171(21):4797-807. doi: 10.1111/bph.12620. Br J Pharmacol. 2014. PMID: 24641481 Free PMC article.

7

NBD-labeled derivatives of the immunomodulatory drug FTY720 as tools for metabolism and mode of action studies.

Ettmayer P, Baumruker T, Guerini D, Mechtcheriakova D, Nussbaumer P, Streiff MB, Billich A. Ettmayer P, et al. Among authors: guerini d. Bioorg Med Chem Lett. 2006 Jan 1;16(1):84-7. doi: 10.1016/j.bmcl.2005.09.038. Epub 2005 Oct 19. Bioorg Med Chem Lett. 2006. PMID: 16236505

8

Constrained azacyclic analogues of the immunomodulatory agent FTY720 as molecular probes for sphingosine 1-phosphate receptors.

Hanessian S, Charron G, Billich A, Guerini D. Hanessian S, et al. Among authors: guerini d. Bioorg Med Chem Lett. 2007 Jan 15;17(2):491-4. doi: 10.1016/j.bmcl.2006.10.014. Epub 2006 Oct 10. Bioorg Med Chem Lett. 2007. PMID: 17070046

9

Novel immunomodulator FTY720 is phosphorylated in rats and humans to form a single stereoisomer. Identification, chemical proof, and biological characterization of the biologically active species and its enantiomer.

Albert R, Hinterding K, Brinkmann V, Guerini D, Müller-Hartwieg C, Knecht H, Simeon C, Streiff M, Wagner T, Welzenbach K, Zécri F, Zollinger M, Cooke N, Francotte E. Albert R, et al. Among authors: guerini d. J Med Chem. 2005 Aug 11;48(16):5373-7. doi: 10.1021/jm050242f. J Med Chem. 2005. PMID: 16078855

10

Synthesis and immobilization of erythro-C14-omega-aminosphingosine-1-phosphate as a potential tool for affinity chromatography.

Ullrich T, Ghobrial M, Peters C, Billich A, Guerini D, Nussbaumer P. Ullrich T, et al. Among authors: guerini d. ChemMedChem. 2008 Feb;3(2):356-60. doi: 10.1002/cmdc.200700285. ChemMedChem. 2008. PMID: 18000941

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