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15 results
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Wnt3a activates dormant c-Kit(-) bone marrow-derived cells with short-term multilineage hematopoietic reconstitution capacity.
Trowbridge JJ, Guezguez B, Moon RT, Bhatia M. Trowbridge JJ, et al. Among authors: guezguez b. Stem Cells. 2010 Aug;28(8):1379-89. doi: 10.1002/stem.457. Stem Cells. 2010. PMID: 20521329 Free article.
GSK3 Deficiencies in Hematopoietic Stem Cells Initiate Pre-neoplastic State that Is Predictive of Clinical Outcomes of Human Acute Leukemia.
Guezguez B, Almakadi M, Benoit YD, Shapovalova Z, Rahmig S, Fiebig-Comyn A, Casado FL, Tanasijevic B, Bresolin S, Masetti R, Doble BW, Bhatia M. Guezguez B, et al. Cancer Cell. 2016 Jan 11;29(1):61-74. doi: 10.1016/j.ccell.2015.11.012. Cancer Cell. 2016. PMID: 26766591 Free article.
Neoplastic human embryonic stem cells as a model of radiation resistance of human cancer stem cells.
Dingwall S, Lee JB, Guezguez B, Fiebig A, McNicol J, Boreham D, Collins TJ, Bhatia M. Dingwall S, et al. Among authors: guezguez b. Oncotarget. 2015 Sep 8;6(26):22258-69. doi: 10.18632/oncotarget.4165. Oncotarget. 2015. PMID: 26082437 Free PMC article.
Pleiotropic roles of Notch signaling in normal, malignant, and developmental hematopoiesis in the human.
Kushwah R, Guezguez B, Lee JB, Hopkins CI, Bhatia M. Kushwah R, et al. Among authors: guezguez b. EMBO Rep. 2014 Nov;15(11):1128-38. doi: 10.15252/embr.201438842. Epub 2014 Sep 24. EMBO Rep. 2014. PMID: 25252682 Free PMC article. Review.
Molecular pathways: epigenetic modulation of Wnt-glycogen synthase kinase-3 signaling to target human cancer stem cells.
Benoit YD, Guezguez B, Boyd AL, Bhatia M. Benoit YD, et al. Among authors: guezguez b. Clin Cancer Res. 2014 Nov 1;20(21):5372-8. doi: 10.1158/1078-0432.CCR-13-2491. Epub 2014 Jul 8. Clin Cancer Res. 2014. PMID: 25006223 Free article. Review.
Driving human-mouse avatars to understand the HSC niche.
Guezguez B, Bhatia M. Guezguez B, et al. Cell Cycle. 2014;13(10):1511-2. doi: 10.4161/cc.28958. Epub 2014 Apr 22. Cell Cycle. 2014. PMID: 24755946 Free PMC article. No abstract available.
Expansive generation of functional airway epithelium from human embryonic stem cells.
McIntyre BA, Alev C, Mechael R, Salci KR, Lee JB, Fiebig-Comyn A, Guezguez B, Wu Y, Sheng G, Bhatia M. McIntyre BA, et al. Among authors: guezguez b. Stem Cells Transl Med. 2014 Jan;3(1):7-17. doi: 10.5966/sctm.2013-0119. Epub 2013 Dec 3. Stem Cells Transl Med. 2014. PMID: 24300555 Free PMC article.
Regional localization within the bone marrow influences the functional capacity of human HSCs.
Guezguez B, Campbell CJ, Boyd AL, Karanu F, Casado FL, Di Cresce C, Collins TJ, Shapovalova Z, Xenocostas A, Bhatia M. Guezguez B, et al. Cell Stem Cell. 2013 Aug 1;13(2):175-89. doi: 10.1016/j.stem.2013.06.015. Cell Stem Cell. 2013. PMID: 23910084 Free article.
Human embryonic stem cell-derived hematopoietic cells maintain core epigenetic machinery of the polycomb group/Trithorax Group complexes distinctly from functional adult hematopoietic stem cells.
Schnerch A, Lee JB, Graham M, Guezguez B, Bhatia M. Schnerch A, et al. Among authors: guezguez b. Stem Cells Dev. 2013 Jan 1;22(1):73-89. doi: 10.1089/scd.2012.0204. Epub 2012 Sep 4. Stem Cells Dev. 2013. PMID: 22800282
Signal control of hematopoietic stem cell fate: Wnt, Notch, and Hedgehog as the usual suspects.
Campbell C, Risueno RM, Salati S, Guezguez B, Bhatia M. Campbell C, et al. Among authors: guezguez b. Curr Opin Hematol. 2008 Jul;15(4):319-25. doi: 10.1097/MOH.0b013e328303b9df. Curr Opin Hematol. 2008. PMID: 18536569
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