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Sensitivity of a renal K+ channel (ROMK2) to the inhibitory sulfonylurea compound glibenclamide is enhanced by coexpression with the ATP-binding cassette transporter cystic fibrosis transmembrane regulator.
McNicholas CM, Guggino WB, Schwiebert EM, Hebert SC, Giebisch G, Egan ME. McNicholas CM, et al. Among authors: guggino wb. Proc Natl Acad Sci U S A. 1996 Jul 23;93(15):8083-8. doi: 10.1073/pnas.93.15.8083. Proc Natl Acad Sci U S A. 1996. PMID: 8755607 Free PMC article.
Both the wild type and a functional isoform of CFTR are expressed in kidney.
Morales MM, Carroll TP, Morita T, Schwiebert EM, Devuyst O, Wilson PD, Lopes AG, Stanton BA, Dietz HC, Cutting GR, Guggino WB. Morales MM, et al. Among authors: guggino wb. Am J Physiol. 1996 Jun;270(6 Pt 2):F1038-48. doi: 10.1152/ajprenal.1996.270.6.F1038. Am J Physiol. 1996. PMID: 8764323
267 results