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Downregulation of mucosal mast cell activation and immune response in diarrhoea-irritable bowel syndrome by oral disodium cromoglycate: A pilot study.
Lobo B, Ramos L, Martínez C, Guilarte M, González-Castro AM, Alonso-Cotoner C, Pigrau M, de Torres I, Rodiño-Janeiro BK, Salvo-Romero E, Fortea M, Pardo-Camacho C, Guagnozzi D, Azpiroz F, Santos J, Vicario M. Lobo B, et al. United European Gastroenterol J. 2017 Oct;5(6):887-897. doi: 10.1177/2050640617691690. Epub 2017 Jan 29. United European Gastroenterol J. 2017. PMID: 29026603 Free PMC article.
Pathogenesis of irritable bowel syndrome: the mast cell connection.
Santos J, Guilarte M, Alonso C, Malagelada JR. Santos J, et al. Scand J Gastroenterol. 2005 Feb;40(2):129-40. doi: 10.1080/00365520410009410. Scand J Gastroenterol. 2005. PMID: 15764142 Review. No abstract available.
Maladaptive intestinal epithelial responses to life stress may predispose healthy women to gut mucosal inflammation.
Alonso C, Guilarte M, Vicario M, Ramos L, Ramadan Z, Antolín M, Martínez C, Rezzi S, Saperas E, Kochhar S, Santos J, Malagelada JR. Alonso C, et al. Gastroenterology. 2008 Jul;135(1):163-172.e1. doi: 10.1053/j.gastro.2008.03.036. Epub 2008 Mar 22. Gastroenterology. 2008. PMID: 18455999
Chronological assessment of mast cell-mediated gut dysfunction and mucosal inflammation in a rat model of chronic psychosocial stress.
Vicario M, Guilarte M, Alonso C, Yang P, Martínez C, Ramos L, Lobo B, González A, Guilà M, Pigrau M, Saperas E, Azpiroz F, Santos J. Vicario M, et al. Brain Behav Immun. 2010 Oct;24(7):1166-75. doi: 10.1016/j.bbi.2010.06.002. Epub 2010 Jun 25. Brain Behav Immun. 2010. PMID: 20600818
Chronic psychosocial stress induces reversible mitochondrial damage and corticotropin-releasing factor receptor type-1 upregulation in the rat intestine and IBS-like gut dysfunction.
Vicario M, Alonso C, Guilarte M, Serra J, Martínez C, González-Castro AM, Lobo B, Antolín M, Andreu AL, García-Arumí E, Casellas M, Saperas E, Malagelada JR, Azpiroz F, Santos J. Vicario M, et al. Psychoneuroendocrinology. 2012 Jan;37(1):65-77. doi: 10.1016/j.psyneuen.2011.05.005. Epub 2011 Jun 8. Psychoneuroendocrinology. 2012. PMID: 21641728
The jejunum of diarrhea-predominant irritable bowel syndrome shows molecular alterations in the tight junction signaling pathway that are associated with mucosal pathobiology and clinical manifestations.
Martínez C, Vicario M, Ramos L, Lobo B, Mosquera JL, Alonso C, Sánchez A, Guilarte M, Antolín M, de Torres I, González-Castro AM, Pigrau M, Saperas E, Azpiroz F, Santos J. Martínez C, et al. Am J Gastroenterol. 2012 May;107(5):736-46. doi: 10.1038/ajg.2011.472. Epub 2012 Mar 13. Am J Gastroenterol. 2012. PMID: 22415197
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