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Page 1
The challenge of new drug discovery for tuberculosis.
Koul A, Arnoult E, Lounis N, Guillemont J, Andries K. Koul A, et al. Among authors: guillemont j. Nature. 2011 Jan 27;469(7331):483-90. doi: 10.1038/nature09657. Nature. 2011. PMID: 21270886 Review.
[R207910 (TMC207): a new antibiotic for the treatment of tuberculosis].
Lounis N, Guillemont J, Veziris N, Koul A, Jarlier V, Andries K. Lounis N, et al. Among authors: guillemont j. Med Mal Infect. 2010 Jul;40(7):383-90. doi: 10.1016/j.medmal.2009.09.007. Epub 2009 Dec 1. Med Mal Infect. 2010. PMID: 19954909 Review. French.
Essentiality of FASII pathway for Staphylococcus aureus.
Balemans W, Lounis N, Gilissen R, Guillemont J, Simmen K, Andries K, Koul A. Balemans W, et al. Among authors: guillemont j. Nature. 2010 Jan 21;463(7279):E3; discussion E4. doi: 10.1038/nature08667. Nature. 2010. PMID: 20090698
Diarylquinolines target subunit c of mycobacterial ATP synthase.
Koul A, Dendouga N, Vergauwen K, Molenberghs B, Vranckx L, Willebrords R, Ristic Z, Lill H, Dorange I, Guillemont J, Bald D, Andries K. Koul A, et al. Among authors: guillemont j. Nat Chem Biol. 2007 Jun;3(6):323-4. doi: 10.1038/nchembio884. Epub 2007 May 13. Nat Chem Biol. 2007. PMID: 17496888
Novel antibiotics targeting respiratory ATP synthesis in Gram-positive pathogenic bacteria.
Balemans W, Vranckx L, Lounis N, Pop O, Guillemont J, Vergauwen K, Mol S, Gilissen R, Motte M, Lançois D, De Bolle M, Bonroy K, Lill H, Andries K, Bald D, Koul A. Balemans W, et al. Among authors: guillemont j. Antimicrob Agents Chemother. 2012 Aug;56(8):4131-9. doi: 10.1128/AAC.00273-12. Epub 2012 May 21. Antimicrob Agents Chemother. 2012. PMID: 22615276 Free PMC article.
A diarylquinoline drug active on the ATP synthase of Mycobacterium tuberculosis.
Andries K, Verhasselt P, Guillemont J, Göhlmann HW, Neefs JM, Winkler H, Van Gestel J, Timmerman P, Zhu M, Lee E, Williams P, de Chaffoy D, Huitric E, Hoffner S, Cambau E, Truffot-Pernot C, Lounis N, Jarlier V. Andries K, et al. Among authors: guillemont j. Science. 2005 Jan 14;307(5707):223-7. doi: 10.1126/science.1106753. Epub 2004 Dec 9. Science. 2005. PMID: 15591164 Clinical Trial.
51 results