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17 results
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mTOR inhibitors in cancer therapy.
Zaytseva YY, Valentino JD, Gulhati P, Evers BM. Zaytseva YY, et al. Among authors: gulhati p. Cancer Lett. 2012 Jun 1;319(1):1-7. doi: 10.1016/j.canlet.2012.01.005. Epub 2012 Jan 17. Cancer Lett. 2012. PMID: 22261336 Review.
Bevacizumab combined with capecitabine and oxaliplatin in patients with advanced adenocarcinoma of the small bowel or ampulla of vater: A single-center, open-label, phase 2 study.
Gulhati P, Raghav K, Shroff RT, Varadhachary GR, Kopetz S, Javle M, Qiao W, Wang H, Morris J, Wolff RA, Overman MJ. Gulhati P, et al. Cancer. 2017 May 15;123(6):1011-1017. doi: 10.1002/cncr.30445. Epub 2016 Nov 14. Cancer. 2017. PMID: 27859010 Free PMC article. Clinical Trial.
Deregulation of Wnt/β-catenin signaling through genetic or epigenetic alterations in human neuroendocrine tumors.
Kim JT, Li J, Jang ER, Gulhati P, Rychahou PG, Napier DL, Wang C, Weiss HL, Lee EY, Anthony L, Townsend CM Jr, Liu C, Evers BM. Kim JT, et al. Among authors: gulhati p. Carcinogenesis. 2013 May;34(5):953-61. doi: 10.1093/carcin/bgt018. Epub 2013 Jan 25. Carcinogenesis. 2013. PMID: 23354304 Free PMC article.
Curcumin inhibits proliferation of colorectal carcinoma by modulating Akt/mTOR signaling.
Johnson SM, Gulhati P, Arrieta I, Wang X, Uchida T, Gao T, Evers BM. Johnson SM, et al. Among authors: gulhati p. Anticancer Res. 2009 Aug;29(8):3185-90. Anticancer Res. 2009. PMID: 19661333 Free PMC article.
Sorafenib enhances the therapeutic efficacy of rapamycin in colorectal cancers harboring oncogenic KRAS and PIK3CA.
Gulhati P, Zaytseva YY, Valentino JD, Stevens PD, Kim JT, Sasazuki T, Shirasawa S, Lee EY, Weiss HL, Dong J, Gao T, Evers BM. Gulhati P, et al. Carcinogenesis. 2012 Sep;33(9):1782-90. doi: 10.1093/carcin/bgs203. Epub 2012 Jun 13. Carcinogenesis. 2012. PMID: 22696593 Free PMC article.
Inhibition of fatty acid synthase attenuates CD44-associated signaling and reduces metastasis in colorectal cancer.
Zaytseva YY, Rychahou PG, Gulhati P, Elliott VA, Mustain WC, O'Connor K, Morris AJ, Sunkara M, Weiss HL, Lee EY, Evers BM. Zaytseva YY, et al. Among authors: gulhati p. Cancer Res. 2012 Mar 15;72(6):1504-17. doi: 10.1158/0008-5472.CAN-11-4057. Epub 2012 Jan 19. Cancer Res. 2012. PMID: 22266115 Free PMC article.
mTORC1 and mTORC2 regulate EMT, motility, and metastasis of colorectal cancer via RhoA and Rac1 signaling pathways.
Gulhati P, Bowen KA, Liu J, Stevens PD, Rychahou PG, Chen M, Lee EY, Weiss HL, O'Connor KL, Gao T, Evers BM. Gulhati P, et al. Cancer Res. 2011 May 1;71(9):3246-56. doi: 10.1158/0008-5472.CAN-10-4058. Epub 2011 Mar 23. Cancer Res. 2011. PMID: 21430067 Free PMC article.
Targeted inhibition of mammalian target of rapamycin signaling inhibits tumorigenesis of colorectal cancer.
Gulhati P, Cai Q, Li J, Liu J, Rychahou PG, Qiu S, Lee EY, Silva SR, Bowen KA, Gao T, Evers BM. Gulhati P, et al. Clin Cancer Res. 2009 Dec 1;15(23):7207-16. doi: 10.1158/1078-0432.CCR-09-1249. Epub 2009 Nov 24. Clin Cancer Res. 2009. PMID: 19934294 Free PMC article.
Novel expression patterns of PI3K/Akt/mTOR signaling pathway components in colorectal cancer.
Johnson SM, Gulhati P, Rampy BA, Han Y, Rychahou PG, Doan HQ, Weiss HL, Evers BM. Johnson SM, et al. Among authors: gulhati p. J Am Coll Surg. 2010 May;210(5):767-76, 776-8. doi: 10.1016/j.jamcollsurg.2009.12.008. J Am Coll Surg. 2010. PMID: 20421047 Free PMC article.
The deubiquitination enzyme USP46 functions as a tumor suppressor by controlling PHLPP-dependent attenuation of Akt signaling in colon cancer.
Li X, Stevens PD, Yang H, Gulhati P, Wang W, Evers BM, Gao T. Li X, et al. Among authors: gulhati p. Oncogene. 2013 Jan 24;32(4):471-8. doi: 10.1038/onc.2012.66. Epub 2012 Mar 5. Oncogene. 2013. PMID: 22391563 Free PMC article.
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