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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1980 4
1981 3
1982 10
1983 4
1984 7
1985 4
1986 12
1987 10
1988 11
1989 14
1990 21
1991 20
1992 41
1993 32
1994 21
1995 35
1996 37
1997 53
1998 51
1999 42
2000 60
2001 58
2002 82
2003 135
2004 181
2005 213
2006 248
2007 286
2008 307
2009 353
2010 475
2011 557
2012 640
2013 754
2014 922
2015 1041
2016 1125
2017 1194
2018 1338
2019 1567
2020 1851
2021 2068
2022 2433
2023 2543
2024 2784
2025 1547
2026 1

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22,518 results

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mtROS-mediated Akt/AMPK/mTOR pathway was involved in Copper-induced autophagy and it attenuates Copper-induced apoptosis in RAW264.7 mouse monocytes.
Luo Q, Song Y, Kang J, Wu Y, Wu F, Li Y, Dong Q, Wang J, Song C, Guo H. Luo Q, et al. Among authors: guo h. Redox Biol. 2021 May;41:101912. doi: 10.1016/j.redox.2021.101912. Epub 2021 Mar 1. Redox Biol. 2021. Retraction in: Redox Biol. 2024 Jul;73:103232. doi: 10.1016/j.redox.2024.103232. PMID: 33706171 Free PMC article. Retracted.
RIPK1 is required for ZBP1-driven necroptosis in human cells.
Amusan OT, Wang S, Yin C, Koehler HS, Li Y, Tenev T, Wilson R, Bellenie B, Zhang T, Wang J, Liu C, Seong K, Poorbaghi SL, Yates J, Shen Y, Upton JW, Meier P, Balachandran S, Guo H. Amusan OT, et al. Among authors: guo h. PLoS Biol. 2025 Feb 21;23(2):e3002845. doi: 10.1371/journal.pbio.3002845. eCollection 2025 Feb. PLoS Biol. 2025. PMID: 39982916 Free PMC article.
A novel, covalent broad-spectrum inhibitor targeting human coronavirus Mpro.
Sun J, Sun D, Yang Q, Wang D, Peng J, Guo H, Ding X, Chen Z, Yuan B, Ivanenkov YA, Yuan J, Zagribelnyy BA, He Y, Su J, Wang L, Tang J, Li Z, Li R, Li T, Hu X, Liang X, Zhu A, Wei P, Fan Y, Liu S, Zheng J, Guan X, Aliper A, Yang M, Bezrukov DS, Xie Z, Terentiev VA, Peng G, Polykovskiy DA, Malyshev AS, Malkov MN, Zhu Q, Aspuru-Guzik A, Ding X, Cai X, Zhang M, Zhao J, Zhong N, Ren F, Chen X, Zhavoronkov A, Zhao J. Sun J, et al. Among authors: guo h. Nat Commun. 2025 May 15;16(1):4546. doi: 10.1038/s41467-025-59870-4. Nat Commun. 2025. PMID: 40374668 Free PMC article.
Conversion of Ku80 K568 crotonylation to SUMOylation facilitates DNA non-homologous end joining and cancer radioresistance.
Zhao H, Gao S, Han Y, Xie D, Xuan L, Huang X, Luo J, Ran Q, Li G, Guo H, Hu W, Jia J, Liu X, Liu Y, Tan J, Bai C, Gu Y, Ma T, Li Z, Guan H, Huang R, Zhou PK. Zhao H, et al. Among authors: guo h. Signal Transduct Target Ther. 2025 Apr 21;10(1):127. doi: 10.1038/s41392-025-02210-1. Signal Transduct Target Ther. 2025. PMID: 40254688 Free PMC article.
22,518 results
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