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8,818 results
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The reciprocal stability of FOXO1 and IRS2 creates a regulatory circuit that controls insulin signaling.
Guo S, Dunn SL, White MF. Guo S, et al. Mol Endocrinol. 2006 Dec;20(12):3389-99. doi: 10.1210/me.2006-0092. Epub 2006 Aug 17. Mol Endocrinol. 2006. PMID: 16916938
Vascular endothelial growth factor activates PI3K/Akt/forkhead signaling in endothelial cells.
Abid MR, Guo S, Minami T, Spokes KC, Ueki K, Skurk C, Walsh K, Aird WC. Abid MR, et al. Among authors: guo s. Arterioscler Thromb Vasc Biol. 2004 Feb;24(2):294-300. doi: 10.1161/01.ATV.0000110502.10593.06. Epub 2003 Dec 1. Arterioscler Thromb Vasc Biol. 2004. PMID: 14656735
Phosphatase and tensin homolog regulation of islet growth and glucose homeostasis.
Kushner JA, Simpson L, Wartschow LM, Guo S, Rankin MM, Parsons R, White MF. Kushner JA, et al. Among authors: guo s. J Biol Chem. 2005 Nov 25;280(47):39388-93. doi: 10.1074/jbc.M504155200. Epub 2005 Sep 16. J Biol Chem. 2005. PMID: 16170201
Forkhead transcription factors inhibit vascular smooth muscle cell proliferation and neointimal hyperplasia.
Abid MR, Yano K, Guo S, Patel VI, Shrikhande G, Spokes KC, Ferran C, Aird WC. Abid MR, et al. Among authors: guo s. J Biol Chem. 2005 Aug 19;280(33):29864-73. doi: 10.1074/jbc.M502149200. Epub 2005 Jun 15. J Biol Chem. 2005. PMID: 15961397
Hepatic suppression of Foxo1 and Foxo3 causes hypoglycemia and hyperlipidemia in mice.
Zhang K, Li L, Qi Y, Zhu X, Gan B, DePinho RA, Averitt T, Guo S. Zhang K, et al. Among authors: guo s. Endocrinology. 2012 Feb;153(2):631-46. doi: 10.1210/en.2011-1527. Epub 2011 Dec 6. Endocrinology. 2012. PMID: 22147007 Free PMC article.
APPL1 potentiates insulin sensitivity by facilitating the binding of IRS1/2 to the insulin receptor.
Ryu J, Galan AK, Xin X, Dong F, Abdul-Ghani MA, Zhou L, Wang C, Li C, Holmes BM, Sloane LB, Austad SN, Guo S, Musi N, DeFronzo RA, Deng C, White MF, Liu F, Dong LQ. Ryu J, et al. Among authors: guo s. Cell Rep. 2014 May 22;7(4):1227-38. doi: 10.1016/j.celrep.2014.04.006. Epub 2014 May 10. Cell Rep. 2014. PMID: 24813896 Free PMC article.
Foxo1 integrates insulin signaling with mitochondrial function in the liver.
Cheng Z, Guo S, Copps K, Dong X, Kollipara R, Rodgers JT, Depinho RA, Puigserver P, White MF. Cheng Z, et al. Among authors: guo s. Nat Med. 2009 Nov;15(11):1307-11. doi: 10.1038/nm.2049. Epub 2009 Oct 18. Nat Med. 2009. PMID: 19838201 Free PMC article.
Inactivation of hepatic Foxo1 by insulin signaling is required for adaptive nutrient homeostasis and endocrine growth regulation.
Dong XC, Copps KD, Guo S, Li Y, Kollipara R, DePinho RA, White MF. Dong XC, et al. Among authors: guo s. Cell Metab. 2008 Jul;8(1):65-76. doi: 10.1016/j.cmet.2008.06.006. Cell Metab. 2008. PMID: 18590693 Free PMC article.
The Irs1 branch of the insulin signaling cascade plays a dominant role in hepatic nutrient homeostasis.
Guo S, Copps KD, Dong X, Park S, Cheng Z, Pocai A, Rossetti L, Sajan M, Farese RV, White MF. Guo S, et al. Mol Cell Biol. 2009 Sep;29(18):5070-83. doi: 10.1128/MCB.00138-09. Epub 2009 Jul 13. Mol Cell Biol. 2009. PMID: 19596788 Free PMC article.
AKT-independent protection of prostate cancer cells from apoptosis mediated through complex formation between the androgen receptor and FKHR.
Li P, Lee H, Guo S, Unterman TG, Jenster G, Bai W. Li P, et al. Among authors: guo s. Mol Cell Biol. 2003 Jan;23(1):104-18. doi: 10.1128/mcb.23.1.104-118.2003. Mol Cell Biol. 2003. PMID: 12482965 Free PMC article.
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