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Population structure of pathogens: the role of immune selection.
Gupta S, Anderson RM. Gupta S, et al. Parasitol Today. 1999 Dec;15(12):497-501. doi: 10.1016/s0169-4758(99)01559-8. Parasitol Today. 1999. PMID: 10557151 Review.
Sunetra Gupta and Roy Anderson discuss how the balance between host immune responses against conserved and variable antigens shapes the population structure of pathogens. ...
Sunetra Gupta and Roy Anderson discuss how the balance between host immune responses against conserved and variable antigens shapes t …
Inferring malaria parasite population structure from serological networks.
Buckee CO, Bull PC, Gupta S. Buckee CO, et al. Proc Biol Sci. 2009 Feb 7;276(1656):477-85. doi: 10.1098/rspb.2008.1122. Proc Biol Sci. 2009. PMID: 18826933 Free PMC article.
Modelling challenges in context: lessons from malaria, HIV, and tuberculosis.
Childs LM, Abuelezam NN, Dye C, Gupta S, Murray MB, Williams BG, Buckee CO. Childs LM, et al. Epidemics. 2015 Mar;10:102-7. doi: 10.1016/j.epidem.2015.02.002. Epub 2015 Feb 16. Epidemics. 2015. PMID: 25843394 Free PMC article.
The effects of tertiary and quaternary infections on the epidemiology of dengue.
Wikramaratna PS, Simmons CP, Gupta S, Recker M. Wikramaratna PS, et al. PLoS One. 2010 Aug 23;5(8):e12347. doi: 10.1371/journal.pone.0012347. PLoS One. 2010. PMID: 20808806 Free PMC article.
Realistic age-prevalent patterns and seroconversion rates are therefore easier reconciled with a low value of dengue's transmission potential if allowing for more than two infections; this should have important consequences for dengue control and intervention measures....
Realistic age-prevalent patterns and seroconversion rates are therefore easier reconciled with a low value of dengue's transmission p …
The effect of immune selection on the structure of the meningococcal opa protein repertoire.
Callaghan MJ, Buckee CO, Jolley KA, Kriz P, Maiden MC, Gupta S. Callaghan MJ, et al. PLoS Pathog. 2008 Mar 14;4(3):e1000020. doi: 10.1371/journal.ppat.1000020. PLoS Pathog. 2008. PMID: 18369470 Free PMC article.
Inverse associations of human leukocyte antigen and malaria parasite types in two West African populations.
Young K, Frodsham A, Doumbo OK, Gupta S, Dolo A, Hu JT, Robson KJ, Crisanti A, Hill AV, Gilbert SC. Young K, et al. Infect Immun. 2005 Feb;73(2):953-5. doi: 10.1128/IAI.73.2.953-955.2005. Infect Immun. 2005. PMID: 15664937 Free PMC article.
Parasite immune escape: new views into host-parasite interactions.
Gupta S. Gupta S. Curr Opin Microbiol. 2005 Aug;8(4):428-33. doi: 10.1016/j.mib.2005.06.011. Curr Opin Microbiol. 2005. PMID: 15993644 Review.
Effects of neutralizing antibodies on escape from CD8+ T-cell responses in HIV-1 infection.
Wikramaratna PS, Lourenço J, Klenerman P, Pybus OG, Gupta S. Wikramaratna PS, et al. Philos Trans R Soc Lond B Biol Sci. 2015 Aug 19;370(1675):20140290. doi: 10.1098/rstb.2014.0290. Philos Trans R Soc Lond B Biol Sci. 2015. PMID: 26150656 Free PMC article.
Role of stochastic processes in maintaining discrete strain structure in antigenically diverse pathogen populations.
Buckee CO, Recker M, Watkins ER, Gupta S. Buckee CO, et al. Proc Natl Acad Sci U S A. 2011 Sep 13;108(37):15504-9. doi: 10.1073/pnas.1102445108. Epub 2011 Aug 29. Proc Natl Acad Sci U S A. 2011. PMID: 21876129 Free PMC article.
Pathogen selection drives nonoverlapping associations between HLA loci.
Penman BS, Ashby B, Buckee CO, Gupta S. Penman BS, et al. Proc Natl Acad Sci U S A. 2013 Nov 26;110(48):19645-50. doi: 10.1073/pnas.1304218110. Epub 2013 Nov 13. Proc Natl Acad Sci U S A. 2013. PMID: 24225852 Free PMC article.
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