Gurkar AU - Search Results

1

Identification of ROCK1 kinase as a critical regulator of Beclin1-mediated autophagy during metabolic stress.

Gurkar AU, Chu K, Raj L, Bouley R, Lee SH, Kim YB, Dunn SE, Mandinova A, Lee SW. Gurkar AU, et al. Nat Commun. 2013;4:2189. doi: 10.1038/ncomms3189. Nat Commun. 2013. PMID: 23877263 Free PMC article.

2

Exonic Variants in Aging-Related Genes Are Predictive of Phenotypic Aging Status.

Breitbach ME, Greenspan S, Resnick NM, Perera S, Gurkar AU, Absher D, Levine AS. Breitbach ME, et al. Among authors: gurkar au. Front Genet. 2019 Dec 19;10:1277. doi: 10.3389/fgene.2019.01277. eCollection 2019. Front Genet. 2019. PMID: 31921313 Free PMC article.

3

Loss of DNA repair mechanisms in cardiac myocytes induce dilated cardiomyopathy.

Henpita C, Vyas R, Healy CL, Kieu TL, Gurkar AU, Yousefzadeh MJ, Cui Y, Lu A, Angelini LA, O'Kelly RD, McGowan SJ, Chandrasekhar S, Vanderpool RR, Hennessy-Wack D, Ross MA, Bachman TN, McTiernan C, Pillai SPS, Ladiges W, Lavasani M, Huard J, Beer-Stolz D, St Croix CM, Watkins SC, Robbins PD, Mora AL, Kelley EE, Wang Y, O'Connell TD, Niedernhofer LJ. Henpita C, et al. Among authors: gurkar au. Aging Cell. 2023 Apr;22(4):e13782. doi: 10.1111/acel.13782. Epub 2023 Feb 3. Aging Cell. 2023. PMID: 36734200 Free PMC article.

4

Selective killing of cancer cells by a small molecule targeting the stress response to ROS.

Raj L, Ide T, Gurkar AU, Foley M, Schenone M, Li X, Tolliday NJ, Golub TR, Carr SA, Shamji AF, Stern AM, Mandinova A, Schreiber SL, Lee SW. Raj L, et al. Among authors: gurkar au. Nature. 2011 Jul 13;475(7355):231-4. doi: 10.1038/nature10167. Nature. 2011. PMID: 21753854 Free PMC article. Retracted.

5

Small-Molecule Reactivation of Mutant p53 to Wild-Type-like p53 through the p53-Hsp40 Regulatory Axis.

Hiraki M, Hwang SY, Cao S, Ramadhar TR, Byun S, Yoon KW, Lee JH, Chu K, Gurkar AU, Kolev V, Zhang J, Namba T, Murphy ME, Newman DJ, Mandinova A, Clardy J, Lee SW. Hiraki M, et al. Among authors: gurkar au. Chem Biol. 2015 Sep 17;22(9):1206-16. doi: 10.1016/j.chembiol.2015.07.016. Epub 2015 Aug 27. Chem Biol. 2015. PMID: 26320861 Free PMC article.

6

Corrigendum: Selective killing of cancer cells by a small molecule targeting the stress response to ROS.

Raj L, Ide T, Gurkar AU, Foley M, Schenone M, Li X, Tolliday NJ, Golub TR, Carr SA, Shamji AF, Stern AM, Mandinova A, Schreiber SL, Lee SW. Raj L, et al. Among authors: gurkar au. Nature. 2015 Oct 22;526(7574):596. doi: 10.1038/nature15370. Epub 2015 Sep 16. Nature. 2015. PMID: 26375002 No abstract available.

7

Retraction Note: Selective killing of cancer cells by a small molecule targeting the stress response to ROS.

Raj L, Ide T, Gurkar AU, Foley M, Schenone M, Li X, Tolliday NJ, Golub TR, Carr SA, Shamji AF, Stern AM, Mandinova A, Schreiber SL, Lee SW. Raj L, et al. Among authors: gurkar au. Nature. 2018 Sep;561(7723):420. doi: 10.1038/s41586-018-0284-y. Nature. 2018. PMID: 30046103 Free PMC article.

8

Rad18-mediated translesion synthesis of bulky DNA adducts is coupled to activation of the Fanconi anemia DNA repair pathway.

Song IY, Palle K, Gurkar A, Tateishi S, Kupfer GM, Vaziri C. Song IY, et al. J Biol Chem. 2010 Oct 8;285(41):31525-36. doi: 10.1074/jbc.M110.138206. Epub 2010 Jul 30. J Biol Chem. 2010. PMID: 20675655 Free PMC article.

9

ERCC1-deficient cells and mice are hypersensitive to lipid peroxidation.

Czerwińska J, Nowak M, Wojtczak P, Dziuban-Lech D, Cieśla JM, Kołata D, Gajewska B, Barańczyk-Kuźma A, Robinson AR, Shane HL, Gregg SQ, Rigatti LH, Yousefzadeh MJ, Gurkar AU, McGowan SJ, Kosicki K, Bednarek M, Zarakowska E, Gackowski D, Oliński R, Speina E, Niedernhofer LJ, Tudek B. Czerwińska J, et al. Among authors: gurkar au. Free Radic Biol Med. 2018 Aug 20;124:79-96. doi: 10.1016/j.freeradbiomed.2018.05.088. Epub 2018 Jun 1. Free Radic Biol Med. 2018. PMID: 29860127 Free PMC article.

10

c-Jun N-terminal kinase-mediated Rad18 phosphorylation facilitates Polη recruitment to stalled replication forks.

Barkley LR, Palle K, Durando M, Day TA, Gurkar A, Kakusho N, Li J, Masai H, Vaziri C. Barkley LR, et al. Mol Biol Cell. 2012 May;23(10):1943-54. doi: 10.1091/mbc.E11-10-0829. Epub 2012 Mar 28. Mol Biol Cell. 2012. PMID: 22456510 Free PMC article.

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