Gutkind JS - Search Results

1

Rare, functional, somatic variants in gene families linked to cancer genes: GPCR signaling as a paradigm.

Raimondi F, Inoue A, Kadji FMN, Shuai N, Gonzalez JC, Singh G, de la Vega AA, Sotillo R, Fischer B, Aoki J, Gutkind JS, Russell RB. Raimondi F, et al. Among authors: gutkind js. Oncogene. 2019 Sep;38(38):6491-6506. doi: 10.1038/s41388-019-0895-2. Epub 2019 Jul 23. Oncogene. 2019. PMID: 31337866 Free PMC article.

2

Kaposi sarcoma-associated herpesvirus promotes tumorigenesis by modulating the Hippo pathway.

Liu G, Yu FX, Kim YC, Meng Z, Naipauer J, Looney DJ, Liu X, Gutkind JS, Mesri EA, Guan KL. Liu G, et al. Among authors: gutkind js. Oncogene. 2015 Jul;34(27):3536-46. doi: 10.1038/onc.2014.281. Epub 2014 Sep 8. Oncogene. 2015. PMID: 25195862 Free PMC article.

3

Inactivating mutations in GNA13 and RHOA in Burkitt's lymphoma and diffuse large B-cell lymphoma: a tumor suppressor function for the Gα13/RhoA axis in B cells.

O'Hayre M, Inoue A, Kufareva I, Wang Z, Mikelis CM, Drummond RA, Avino S, Finkel K, Kalim KW, DiPasquale G, Guo F, Aoki J, Zheng Y, Lionakis MS, Molinolo AA, Gutkind JS. O'Hayre M, et al. Among authors: gutkind js. Oncogene. 2016 Jul 21;35(29):3771-80. doi: 10.1038/onc.2015.442. Epub 2015 Nov 30. Oncogene. 2016. PMID: 26616858 Free PMC article.

4

Onco-GPCR signaling and dysregulated expression of microRNAs in human cancer.

Nohata N, Goto Y, Gutkind JS. Nohata N, et al. Among authors: gutkind js. J Hum Genet. 2017 Jan;62(1):87-96. doi: 10.1038/jhg.2016.124. Epub 2016 Oct 13. J Hum Genet. 2017. PMID: 27734836 Review.

5

Epidermal loss of Gαq confers a migratory and differentiation defect in keratinocytes.

Doçi CL, Mikelis CM, Callejas-Valera JL, Hansen KK, Molinolo AA, Inoue A, Offermanns S, Gutkind JS. Doçi CL, et al. Among authors: gutkind js. PLoS One. 2017 Mar 16;12(3):e0173692. doi: 10.1371/journal.pone.0173692. eCollection 2017. PLoS One. 2017. PMID: 28301547 Free PMC article.

6

Genetic evidence that β-arrestins are dispensable for the initiation of β₂-adrenergic receptor signaling to ERK.

O'Hayre M, Eichel K, Avino S, Zhao X, Steffen DJ, Feng X, Kawakami K, Aoki J, Messer K, Sunahara R, Inoue A, von Zastrow M, Gutkind JS. O'Hayre M, et al. Among authors: gutkind js. Sci Signal. 2017 Jun 20;10(484):eaal3395. doi: 10.1126/scisignal.aal3395. Sci Signal. 2017. PMID: 28634209 Free PMC article.

7

Genetic variants affecting equivalent protein family positions reflect human diversity.

Raimondi F, Betts MJ, Lu Q, Inoue A, Gutkind JS, Russell RB. Raimondi F, et al. Among authors: gutkind js. Sci Rep. 2017 Oct 6;7(1):12771. doi: 10.1038/s41598-017-12971-7. Sci Rep. 2017. PMID: 28986545 Free PMC article.

8

Direct targeting of Gα_q and Gα₁₁ oncoproteins in cancer cells.

Annala S, Feng X, Shridhar N, Eryilmaz F, Patt J, Yang J, Pfeil EM, Cervantes-Villagrana RD, Inoue A, Häberlein F, Slodczyk T, Reher R, Kehraus S, Monteleone S, Schrage R, Heycke N, Rick U, Engel S, Pfeifer A, Kolb P, König G, Bünemann M, Tüting T, Vázquez-Prado J, Gutkind JS, Gaffal E, Kostenis E. Annala S, et al. Among authors: gutkind js. Sci Signal. 2019 Mar 19;12(573):eaau5948. doi: 10.1126/scisignal.aau5948. Sci Signal. 2019. PMID: 30890659

9

PRECOG: PREdicting COupling probabilities of G-protein coupled receptors.

Singh G, Inoue A, Gutkind JS, Russell RB, Raimondi F. Singh G, et al. Among authors: gutkind js. Nucleic Acids Res. 2019 Jul 2;47(W1):W395-W401. doi: 10.1093/nar/gkz392. Nucleic Acids Res. 2019. PMID: 31143927 Free PMC article.

10

Illuminating G-Protein-Coupling Selectivity of GPCRs.

Inoue A, Raimondi F, Kadji FMN, Singh G, Kishi T, Uwamizu A, Ono Y, Shinjo Y, Ishida S, Arang N, Kawakami K, Gutkind JS, Aoki J, Russell RB. Inoue A, et al. Among authors: gutkind js. Cell. 2019 Jun 13;177(7):1933-1947.e25. doi: 10.1016/j.cell.2019.04.044. Epub 2019 May 31. Cell. 2019. PMID: 31160049 Free PMC article.

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